| Gene Symbol |
CHRAC1
|
| Entrez Gene |
54108
|
| Alt Symbol |
CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromatin accessibility complex 1
|
| Other Description |
DNA polymerase epsilon subunit p15|chromatin accessibility complex 15 kDa protein|chromatin accessibility complex protein 1|histone-fold protein CHRAC15
|
| Swissprots |
Q9NRG0
|
| Accessions |
EAW92206 Q9NRG0 AF226076 AAF72416 AK023537 BAB14601 AK308709 AK311595 AL543044 BC015891 AAH15891 BU160855 DA647606 DA887467 DQ895620 ABM86546 EU176214 ABW03665 NM_017444 NP_059140 NR_023360 NR_040712
|
| Function |
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
|
![Western Blot: CHRAC1 Overexpression Lysate (Adult Normal) [NBL1-09170] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CHRAC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5854_CHRAC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09170-img0002.jpg)