Gene Symbol | COL5A1 |
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Entrez Gene | 1289 |
Alt Symbol | EDSC |
Species | Human |
Gene Type | protein-coding |
Description | collagen, type V, alpha 1 |
Other Description | collagen alpha-1(V) chain |
Swissprots | Q15094 Q5SUX4 P20908 |
Accessions | AAA79853 CCQ42964 CDM55398 CDM55579 EAW88128 EAW88129 EAW88130 EAW88131 EAW88132 P20908 AB209864 BAD93101 AB371583 BAG48312 AI190929 AK057231 AK122763 AK127662 BC008760 AAH08760 BC032405 BM051019 CA446007 CB152831 CN399198 CN399221 CN399265 CN484933 D90279 BAA14323 ES314363 XR_929712 XR_929713 NM_000093 NP_000084 NM_001278074 NP_001265003 |
Function | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway |
COL5A1 CRISPR/Cas9 KO Plasmid (h) - sc-401579 from Santa Cruz Biotechnology
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COL5A1 HDR Plasmid (h) - sc-401579-HDR from Santa Cruz Biotechnology
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COL5A1 Double Nickase Plasmid (h) - sc-401579-NIC from Santa Cruz Biotechnology
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COL5A1 Double Nickase Plasmid (h2) - sc-401579-NIC-2 from Santa Cruz Biotechnology
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COL5A1 CRISPR Activation Plasmid (h) - sc-401579-ACT from Santa Cruz Biotechnology
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COL5A1 CRISPR Activation Plasmid (h2) - sc-401579-ACT-2 from Santa Cruz Biotechnology
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COL5A1 Lentiviral Activation Particles (h) - sc-401579-LAC from Santa Cruz Biotechnology
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COL5A1 Lentiviral Activation Particles (h2) - sc-401579-LAC-2 from Santa Cruz Biotechnology
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COL5A1 siRNA (h) - sc-35083 from Santa Cruz Biotechnology
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COL5A1 shRNA Plasmid (h) - sc-35083-SH from Santa Cruz Biotechnology
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COL5A1 shRNA (h) Lentiviral Particles - sc-35083-V from Santa Cruz Biotechnology
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Collagen V RNAi - H00001289-R01 from Novus Biologicals
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MISSION® esiRNA - EHU091401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6396 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6396 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11539 from Sigma-Aldrich
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COL5A1 siRNA (Human) - CRH0903 from Cohesion Biosciences
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COL5A1 - MBS8232303 from MyBioSource
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shRNA set against Human COL5A1 (NM_000093.3) - SHH267341 from Creative biogene
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shRNA set against Human COL5A1(NM_000093.3) - SHG190689 from Creative biogene
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Human COL5A1 siRNA - orb261405 from Biorbyt
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COL5A1 shRNA Plasmid (Human) - CHH0903 from Cohesion Biosciences
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COL5A1 miRNA 3'UTR clone - MiUTR1H-02325 from Creative biogene
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