| Gene Symbol |
GRAMD4
|
| Entrez Gene |
23151
|
| Alt Symbol |
DIP, dA59H18.1, dJ439F8.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GRAM domain containing 4
|
| Other Description |
GRAM domain-containing protein 4|death-inducing protein|death-inducing-protein
|
| Swissprots |
A9IN57 Q9UGE6 Q68EN0 Q9Y4B9 A9IN51 Q6IC98
|
| Accessions |
CBX47426 EAW73432 EAW73433 EAW73434 EAW73435 EAW73436 EAW73437 Q6IC98 AB018310 BAA34487 AI399959 AL137628 BC011984 BC033170 BC063558 BC080189 AAH80189 BC129837 AAI29838 CR456470 CAG30356 R39786 XM_005261396 XP_005261453 XM_005261398 XP_005261455 XM_006724169 XP_006724232 XM_006724170 XP_006724233 XM_011530011 XP_011528313 XM_011530012 XP_011528314 XM_011530013 XP_011528315 XM_011530014 XP_011528316 NM_015124 NP_055939
|
| Function |
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. {ECO:0000269|PubMed:15565177}.
|
| Subcellular Location |
Mitochondrion membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=Colocalizes with COX4I1. {ECO:0000269|PubMed:15565177}.
|
| Tissue Specificity |
Expressed in lung and in primary lung squamous cell carcinoma (LSCC). {ECO:0000269|PubMed:18302964}.
|