PAX3
| Gene Symbol | PAX3 |
|---|---|
| Entrez Gene | 5077 |
| Alt Symbol | CDHS, HUP2, WS1, WS3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | paired box 3 |
| Other Description | paired box homeotic gene 3|paired box protein Pax-3|paired domain gene 3|paired domain gene HuP2 |
| Swissprots | Q494Z4 Q86UQ2 Q6GSJ9 P23760 Q86UQ3 Q494Z3 Q16448 G5E9C1 Q53T90 |
| Accessions | AAA80573 AAA80574 AAA91849 AAB21476 AAB26807 AAY14900 ACU00135 CAA33145 EAW70789 EAW70790 EAW70791 EAW70792 EAW70793 EAW70794 EAW70795 EAW70796 EAW70797 P23760 AI382779 AI399816 AK291278 BAF83967 AY251279 AAP13872 AY251280 AAP13873 BC063547 AAH63547 BC101299 AAI01300 BC101300 AAI01301 BC101301 AAI01302 BC101302 AAI01303 BC114363 AAI14364 CA389778 DA758804 DN989642 EU446645 ABZ92174 L07483 S69369 AAB30167 S69370 AAB30168 U02309 AAA03628 XM_011511278 XP_011509580 XM_011511279 XP_011509581 XM_011511280 XP_011509582 XM_011511281 XP_011509583 NM_000438 NP_000429 NM_001127366 NP_001120838 NM_013942 NP_039230 NM_181457 NP_852122 NM_181458 NP_852123 NM_181459 NP_852124 NM_181460 NP_852125 NM_181461 NP_852126 |
| Function | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. {ECO:0000269|PubMed:16951170}. |
| Subcellular Location | Nucleus. |
| Top Pathways | Transcriptional misregulation in cancer |
Pax-3 CRISPR/Cas9 KO Plasmid (h) - sc-401657 from Santa Cruz Biotechnology
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Pax-3 HDR Plasmid (h) - sc-401657-HDR from Santa Cruz Biotechnology
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Pax-3 Double Nickase Plasmid (h) - sc-401657-NIC from Santa Cruz Biotechnology
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Pax-3 Double Nickase Plasmid (h2) - sc-401657-NIC-2 from Santa Cruz Biotechnology
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Pax-3 CRISPR Activation Plasmid (h) - sc-401657-ACT from Santa Cruz Biotechnology
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Pax-3 CRISPR Activation Plasmid (h2) - sc-401657-ACT-2 from Santa Cruz Biotechnology
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Pax-3 Lentiviral Activation Particles (h) - sc-401657-LAC from Santa Cruz Biotechnology
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Pax-3 Lentiviral Activation Particles (h2) - sc-401657-LAC-2 from Santa Cruz Biotechnology
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Pax-3 siRNA (h) - sc-38747 from Santa Cruz Biotechnology
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Pax-3 shRNA Plasmid (h) - sc-38747-SH from Santa Cruz Biotechnology
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Pax-3 shRNA (h) Lentiviral Particles - sc-38747-V from Santa Cruz Biotechnology
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Pax3 RNAi - H00005077-R04 from Novus Biologicals
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Pax3 RNAi - H00005077-R07 from Novus Biologicals
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Pax3 RNAi - H00005077-R02 from Novus Biologicals
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Pax3 RNAi - H00005077-R06 from Novus Biologicals
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Pax3 RNAi - H00005077-R03 from Novus Biologicals
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MISSION® esiRNA - EHU132501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16371 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09619 from Sigma-Aldrich
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PAX3 siRNA (Human) - CRH3375 from Cohesion Biosciences
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Pax3 RNAi - H00005077-R01 from Novus Biologicals
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Pax3 RNAi - H00005077-R05 from Novus Biologicals
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Pax-3 CRISPR/Cas9 KO Plasmid (h2) - sc-401657-KO-2 from Santa Cruz Biotechnology
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Pax-3 HDR Plasmid (h2) - sc-401657-HDR-2 from Santa Cruz Biotechnology
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