Gene Symbol | INHBE |
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Entrez Gene | 83729 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | inhibin, beta E |
Other Description | activin beta E|activin beta-E chain|inhibin beta E chain |
Swissprots | P58166 |
Accessions | CAF86622 EAW97012 P58166 AF412024 AAN03682 AK075285 BAC11521 AK308647 BC005161 AAH05161 BF305618 EU831419 ACE87106 EU831512 ACE86431 JF432681 ADZ15898 NM_031479 NP_113667 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Inhibin β-E siRNA (h) - sc-75338 from Santa Cruz Biotechnology
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Inhibin β-E shRNA Plasmid (h) - sc-75338-SH from Santa Cruz Biotechnology
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Inhibin β-E shRNA (h) Lentiviral Particles - sc-75338-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10680 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10680 from Sigma-Aldrich
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INHBE siRNA (Human) - CRJ3179 from Cohesion Biosciences
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INHBE - MBS8216313 from MyBioSource
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shRNA set against Human INHBE(NM_031479.3) - SHL178208 from Creative biogene
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Human INHBE siRNA - orb273680 from Biorbyt
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INHBE shRNA Plasmid (Human) - CHJ3179 from Cohesion Biosciences
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INHBE miRNA 3'UTR clone - MiUTR1H-04951 from Creative biogene
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