| Gene Symbol |
ORMDL1
|
| Entrez Gene |
94101
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ORMDL sphingolipid biosynthesis regulator 1
|
| Other Description |
ORM1-like protein 1|adoplin-1
|
| Swissprots |
D3DPH9 B2R8W3 Q9P0S3
|
| Accessions |
AAM43502 AAY14772 CAF85924 CAF86890 CAJ42732 EAX10887 EAX10888 EAX10889 Q9P0S3 AA603217 AB064959 BAC11710 AB064960 BAC11711 AF151036 AAF36122 AF395704 AAM43503 AI674061 AK074756 BAC11184 AK075160 BAC11441 AK126336 AK313533 BAG36310 BC005200 AAH05200 CR936635 CAI56776 DB122266 JF432550 ADZ15767 XM_005246970 XP_005247027 XM_011512198 XP_011510500 XM_011512199 XP_011510501 XM_011512200 XP_011510502 NM_001128150 NP_001121622 NM_016467 NP_057551
|
| Function |
Negative regulator of sphingolipid synthesis. {ECO:0000269|PubMed:20182505}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374}.
|
| Tissue Specificity |
Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. Expressed at intermediate level in pancreas, placenta and brain but low in skeletal muscle and lung. {ECO:0000269|PubMed:12093374}.
|