Gene Symbol | MYH7B |
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Entrez Gene | 57644 |
Alt Symbol | MHC14, MYH14 |
Species | Human |
Gene Type | protein-coding |
Description | myosin, heavy chain 7B, cardiac muscle, beta |
Other Description | U937-associated antigen|antigen MLAA-21|myosin heavy chain 7B, cardiac muscle beta isoform|myosin, heavy polypeptide 7B, cardiac muscle, beta|myosin-7B|slow A MYH14 |
Swissprots | Q6NT44 Q9NWE2 Q9P216 Q6NT57 A7E2Y1 Q96I57 Q6WG75 Q5JVW7 |
Accessions | A7E2Y1 EAW76236 EAW76237 EAW76238 AB040945 BAA96036 AK000947 BAA91440 BC007808 AAH07808 BC069327 AAH69327 BC069406 AAH69406 BC151242 AAI51243 BG189104 DB484143 XM_006723840 XP_006723903 XM_011528941 XP_011527243 XM_011528942 XP_011527244 XM_011528943 XP_011527245 XM_011528944 XP_011527246 XM_011528945 XP_011527247 XM_011528946 XP_011527248 XM_011528947 XP_011527249 XM_011528948 XP_011527250 XM_011528949 XP_011527251 XM_011528950 XP_011527252 NM_020884 NP_065935 |
Function | Involved in muscle contraction. {ECO:0000269|PubMed:11919279}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:15755502}; Peripheral membrane protein {ECO:0000269|PubMed:15755502}. |
Tissue Specificity | Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen and liver. {ECO:0000269|PubMed:10819331}. |
Top Pathways | Tight junction |
MYH7B CRISPR/Cas9 KO Plasmid (h) - sc-400621 from Santa Cruz Biotechnology
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MYH7B HDR Plasmid (h) - sc-400621-HDR from Santa Cruz Biotechnology
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MYH7B Double Nickase Plasmid (h) - sc-400621-NIC from Santa Cruz Biotechnology
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MYH7B Double Nickase Plasmid (h2) - sc-400621-NIC-2 from Santa Cruz Biotechnology
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MYH7B CRISPR Activation Plasmid (h) - sc-400621-ACT from Santa Cruz Biotechnology
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MYH7B CRISPR Activation Plasmid (h2) - sc-400621-ACT-2 from Santa Cruz Biotechnology
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MYH7B Lentiviral Activation Particles (h) - sc-400621-LAC from Santa Cruz Biotechnology
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MYH7B Lentiviral Activation Particles (h2) - sc-400621-LAC-2 from Santa Cruz Biotechnology
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MYH7B siRNA (h) - sc-75848 from Santa Cruz Biotechnology
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MYH7B shRNA Plasmid (h) - sc-75848-SH from Santa Cruz Biotechnology
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MYH7B shRNA (h) Lentiviral Particles - sc-75848-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU139781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14824 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14824 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01603 from Sigma-Aldrich
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MYH7B siRNA (Human) - CRJ1602 from Cohesion Biosciences
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MYH7B CRISPR/Cas9 KO Plasmid (h2) - sc-400621-KO-2 from Santa Cruz Biotechnology
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MYH7B HDR Plasmid (h2) - sc-400621-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MYH7B (NM_020884.3) - SHH347836 from Creative biogene
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Human MYH7B siRNA - orb272103 from Biorbyt
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MYH7B shRNA Plasmid (Human) - CHJ1602 from Cohesion Biosciences
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MYH7B miRNA 3'UTR clone - MiUTR3H-10899 from Creative biogene
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