Gene Symbol | ZXDC |
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Entrez Gene | 79364 |
Alt Symbol | ZXDL |
Species | Human |
Gene Type | protein-coding |
Description | ZXD family zinc finger C |
Other Description | SERH2790|ZXD-like zinc finger protein|zinc finger protein ZXDC |
Swissprots | Q7L3L1 Q2QGD7 Q8NAU2 Q6DKI8 C5J0H9 |
Accessions | EAW79361 Q2QGD7 AF131763 AK023923 BAB14726 AK092101 BAC03805 AK093796 AK095149 AK098501 AL390142 CAH10665 AW512405 AY277596 AAQ18035 AY358102 AAQ88469 AY936556 AAX23974 BC002940 AAH02940 BC012729 AAH12729 BC063713 BC073859 AAH73859 BC110644 BM686637 CB268797 DQ079590 AAZ30918 EU446527 ABZ92056 FJ980275 ACR56328 XM_005247757 XP_005247814 XM_006713741 XP_006713804 XM_011513119 XP_011511421 XR_924168 XR_924169 XR_924170 NM_001040653 NP_001035743 NM_025112 NP_079388 NR_104249 |
Function | Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. {ECO:0000269|PubMed:16600381, ECO:0000269|PubMed:17493635, ECO:0000269|PubMed:17696781}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen. {ECO:0000269|PubMed:16600381}. |
ZXDC CRISPR/Cas9 KO Plasmid (h) - sc-413162 from Santa Cruz Biotechnology
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ZXDC HDR Plasmid (h) - sc-413162-HDR from Santa Cruz Biotechnology
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ZXDC Double Nickase Plasmid (h) - sc-413162-NIC from Santa Cruz Biotechnology
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ZXDC Double Nickase Plasmid (h2) - sc-413162-NIC-2 from Santa Cruz Biotechnology
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ZXDC CRISPR Activation Plasmid (h) - sc-413162-ACT from Santa Cruz Biotechnology
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ZXDC CRISPR Activation Plasmid (h2) - sc-413162-ACT-2 from Santa Cruz Biotechnology
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ZXDC Lentiviral Activation Particles (h) - sc-413162-LAC from Santa Cruz Biotechnology
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ZXDC Lentiviral Activation Particles (h2) - sc-413162-LAC-2 from Santa Cruz Biotechnology
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ZXDC siRNA (h) - sc-78259 from Santa Cruz Biotechnology
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ZXDC shRNA Plasmid (h) - sc-78259-SH from Santa Cruz Biotechnology
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ZXDC shRNA (h) Lentiviral Particles - sc-78259-V from Santa Cruz Biotechnology
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ZXDC RNAi - H00079364-R01 from Novus Biologicals
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MISSION® esiRNA - EHU047851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23826 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23826 from Sigma-Aldrich
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ZXDC siRNA (Human) - CRJ2372 from Cohesion Biosciences
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ZXDC - MBS8226946 from MyBioSource
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shRNA set against Human ZXDC(NM_025112.4) - SHL163926 from Creative biogene
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Human ZXDC siRNA - orb272873 from Biorbyt
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ZXDC shRNA Plasmid (Human) - CHJ2372 from Cohesion Biosciences
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ZXDC miRNA 3'UTR clone - MiUTR1H-11775 from Creative biogene
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