| Gene Symbol |
RNF138
|
| Entrez Gene |
51444
|
| Alt Symbol |
HSD-4, NARF, STRIN, hNARF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 138, E3 ubiquitin protein ligase
|
| Other Description |
E3 ubiquitin-protein ligase RNF138|NLK-associated RING finger protein|Nemo-like kinase-associated RING finger protein|nemo-like kinase associated ring finger protein
|
| Swissprots |
Q9UF87 Q9H8K2 Q8WVD3 Q9UKI6 B2RE17
|
| Accessions |
CAE91797 EAX01280 EAX01281 EAX01282 EAX01283 Q8WVD3 AF162680 AAD46623 AK023579 BAB14614 AK315761 BAG38114 AL133557 CAB63712 BC018107 AAH18107 BI461242 BI463820 BM564125 BT006878 AAP35524 BU662580 CR457150 CAG33431 DA752192 DB091985 DB452430 DQ890744 ABM81670 DQ893914 ABM84840 XM_005258285 XP_005258342 XM_005258286 XP_005258343 XR_935225 NM_001191324 NP_001178253 NM_016271 NP_057355 NM_198128 NP_937761
|
| Function |
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway. {ECO:0000269|PubMed:16714285}.
|
