Gene Symbol |
TUSC5
|
Entrez Gene |
286753
|
Alt Symbol |
DSPB1, IFITMD3, LOST1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
tumor suppressor candidate 5
|
Other Description |
dispanin subfamily B member 1|interferon induced transmembrane protein domain containing 3|interferon-induced transmembrane domain-containing protein D3|located at seventeen p thirteen point three 1|protein located at seventeen-p-thirteen point three 1
|
Swissprots |
Q8IXB3 A6NMK4
|
Accessions |
EAW90630 Q8IXB3 AB090231 BAC43751 AL831929 BC142615 AAI42616 NM_172367 NP_758955
|
Function |
May be involved in fat metabolism. {ECO:0000250}.
|
Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus. {ECO:0000269|PubMed:12660825}.
|