| Gene Symbol |
MAPRE2
|
| Entrez Gene |
10982
|
| Alt Symbol |
EB1, EB2, RP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
microtubule-associated protein, RP/EB family, member 2
|
| Other Description |
APC-binding protein EB1|APC-binding protein EB2|T-cell activation protein, EB1 family|end-binding protein 2|microtubule-associated protein RP/EB family member 2
|
| Swissprots |
Q9UQ33 G5E9I6 B2RE21 Q15555 B7Z2L3 F5H1V8 E9PHR3 B4DJV4 B3KR39
|
| Accessions |
CBX47563 EAX01336 EAX01337 EAX01338 EAX01339 EAX01340 Q15555 AB016823 BAA83375 AK090945 BAG52251 AK294833 BAH11899 AK296251 BAG58966 AK315766 BAG38118 AM393705 CAL38581 BC007318 AAH07318 BM673789 BT020086 AAV38889 CR536545 CAG38782 DC335558 DC341673 DC354326 DQ892923 ABM83849 DQ896172 ABM87171 DR422766 X94232 CAA63923 XM_006722375 XP_006722438 XM_011525795 XP_011524097 NM_001143826 NP_001137298 NM_001143827 NP_001137299 NM_001256420 NP_001243349 NM_014268 NP_055083 NR_046177
|
| Function |
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10188731}. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules.
|
| Tissue Specificity |
Expressed in different tumor cell lines. Up- regulated in activated B- and T-lymphocytes. {ECO:0000269|PubMed:9233623}.
|
![Western Blot: EB2 Overexpression Lysate (Adult Normal) [NBL1-12892] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EB2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9001_EB2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12892-img0002.jpg)