Gene Symbol | MCAT |
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Entrez Gene | 27349 |
Alt Symbol | FASN2C, MCT, MT, NET62, fabD |
Species | Human |
Gene Type | protein-coding |
Description | malonyl CoA:ACP acyltransferase (mitochondrial) |
Other Description | [Acyl-carrier-protein] malonyltransferase|malonyl-CoA-acyl carrier protein transacylase, mitochondrial|malonyl-CoA:acyl carrier protein transacylase, mitochondrial|mitochondrial malonyl CoA:ACP acyltransferase|mitochondrial malonyltransferase |
Swissprots | O95511 B0QY72 O95510 Q8IVS2 |
Accessions | CAA18261 CAQ07851 EAW73286 EAW73287 Q8IVS2 AA402283 AI811069 AK314059 BAG36765 AL359401 CAB94789 AL359403 CAB94790 BC030985 AAH30985 BC042195 AAH42195 BI464466 BX111669 CA422238 DB306307 XM_011530156 XP_011528458 NM_014507 NP_055322 NM_173467 NP_775738 NR_046423 |
Function | Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias. {ECO:0000269|PubMed:12882974}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:12882974}. |
Top Pathways | Fatty acid biosynthesis, Fatty acid metabolism |
MCAT CRISPR/Cas9 KO Plasmid (h) - sc-404338 from Santa Cruz Biotechnology
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MCAT HDR Plasmid (h) - sc-404338-HDR from Santa Cruz Biotechnology
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MCAT Double Nickase Plasmid (h) - sc-404338-NIC from Santa Cruz Biotechnology
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MCAT Double Nickase Plasmid (h2) - sc-404338-NIC-2 from Santa Cruz Biotechnology
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MCAT CRISPR Activation Plasmid (h) - sc-404338-ACT from Santa Cruz Biotechnology
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MCAT CRISPR Activation Plasmid (h2) - sc-404338-ACT-2 from Santa Cruz Biotechnology
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MCAT Lentiviral Activation Particles (h) - sc-404338-LAC from Santa Cruz Biotechnology
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MCAT Lentiviral Activation Particles (h2) - sc-404338-LAC-2 from Santa Cruz Biotechnology
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MCAT siRNA (h) - sc-75760 from Santa Cruz Biotechnology
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MCAT shRNA Plasmid (h) - sc-75760-SH from Santa Cruz Biotechnology
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MCAT shRNA (h) Lentiviral Particles - sc-75760-V from Santa Cruz Biotechnology
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MCAT RNAi - H00027349-R01 from Novus Biologicals
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MCAT RNAi - H00027349-R02 from Novus Biologicals
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MISSION® esiRNA - EHU099841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13103 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13103 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08741 from Sigma-Aldrich
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MCAT siRNA (Human) - CRH9098 from Cohesion Biosciences
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MCAT CRISPR/Cas9 KO Plasmid (h2) - sc-404338-KO-2 from Santa Cruz Biotechnology
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MCAT HDR Plasmid (h2) - sc-404338-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MCAT (NM_173467.4) - SHH339131 from Creative biogene
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shRNA set against Human MCAT(NM_014507.3) - SHH180641 from Creative biogene
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shRNA set against Human MCAT(NM_173467.4) - SHH180659 from Creative biogene
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Human MCAT siRNA - orb269600 from Biorbyt
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MCAT shRNA Plasmid (Human) - CHH9098 from Cohesion Biosciences
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