| Gene Symbol |
CLGN
|
| Entrez Gene |
1047
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calmegin
|
| Other Description |
-
|
| Swissprots |
D3DNY8 O14967 B4DXV8 B3KS90
|
| Accessions |
CCQ43260 EAX05099 EAX05100 EAX05101 O14967 AK093096 BAG52652 AK290819 BAF83508 AK299243 BAG61274 AK302149 BAG63520 AL045602 BC028357 AAH28357 D86322 BAA22590 DC396076 DQ892100 ABM83026 DQ895295 ABM86221 NM_001130675 NP_001124147 NM_004362 NP_004353
|
| Function |
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Detected in testis (at protein level). Detected in testis. {ECO:0000269|PubMed:9434179}.
|
![Western Blot: CLGN Overexpression Lysate (Adult Normal) [NBL1-09265] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CLGN.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1522_CLGN%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09265-img0002.jpg)
![Western Blot: CLGN Overexpression Lysate (Adult Normal) [NBP2-09516] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CLGN.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24726_CLGN%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-09516-img0001.jpg)