Gene Symbol | PARVG |
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Entrez Gene | 64098 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | parvin, gamma |
Other Description | gamma-parvin |
Swissprots | Q9BQX5 B4DDW5 Q9NSG1 E7EVM6 Q9HBI0 |
Accessions | EAW73332 EAW73333 EAW73334 EAW73335 EAW73336 Q9HBI0 AF237772 AAG27174 AI075834 AK225929 AK293360 BAG56876 AK307294 AK307299 AK309348 AK310087 AK311264 AL355092 CAB90188 AL590887 CAC37414 BC034406 AAH34406 BI818662 BP299653 BP299720 BX648942 CA440742 CR456480 CAG30366 CU013030 CAK54461 CU013318 CAK54760 DA673498 DA946316 XM_005261702 XP_005261759 XM_011530301 XP_011528603 XM_011530302 XP_011528604 XM_011530303 XP_011528605 XM_011530304 XP_011528606 XM_011530305 XP_011528607 XM_011530306 XP_011528608 XM_011530307 XP_011528609 NM_001137606 NM_001254741 NM_001254742 NM_001254743 NM_001137605 NP_001131077 NM_022141 NP_071424 |
Function | Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. {ECO:0000250}. |
Subcellular Location | Cell junction, focal adhesion. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Constituent of focal adhesions. {ECO:0000250}. |
Tissue Specificity | Expressed predominantly in lymphoid organs, including spleen, thymus, lymph node, bone marrow and peripheral blood leukocytes and moderately in the digestive tract, including stomach, duodenum, jejunum, ileum, ileocecum and appendix, as well as in lung and liver. Also expressed in tumors, but at a lower level than in the corresponding normal tissues. {ECO:0000269|PubMed:11722847}. |
Top Pathways | Focal adhesion |
γ-parvin CRISPR/Cas9 KO Plasmid (h) - sc-412979 from Santa Cruz Biotechnology
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γ-parvin HDR Plasmid (h) - sc-412979-HDR from Santa Cruz Biotechnology
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γ-parvin Double Nickase Plasmid (h) - sc-412979-NIC from Santa Cruz Biotechnology
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γ-parvin Double Nickase Plasmid (h2) - sc-412979-NIC-2 from Santa Cruz Biotechnology
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γ-parvin CRISPR Activation Plasmid (h) - sc-412979-ACT from Santa Cruz Biotechnology
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γ-parvin CRISPR Activation Plasmid (h2) - sc-412979-ACT-2 from Santa Cruz Biotechnology
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γ-parvin Lentiviral Activation Particles (h) - sc-412979-LAC from Santa Cruz Biotechnology
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γ-parvin Lentiviral Activation Particles (h2) - sc-412979-LAC-2 from Santa Cruz Biotechnology
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γ-parvin siRNA (h) - sc-61302 from Santa Cruz Biotechnology
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γ-parvin shRNA Plasmid (h) - sc-61302-SH from Santa Cruz Biotechnology
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γ-parvin shRNA (h) Lentiviral Particles - sc-61302-V from Santa Cruz Biotechnology
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Parvin gamma RNAi - H00064098-R01 from Novus Biologicals
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MISSION® esiRNA - EHU072831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16358 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16358 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01088 from Sigma-Aldrich
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PARVG siRNA (Human) - CRJ1918 from Cohesion Biosciences
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shRNA set against Human PARVG (NM_022141.5) - SHH370996 from Creative biogene
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Human PARVG siRNA - orb272419 from Biorbyt
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PARVG shRNA Plasmid (Human) - CHJ1918 from Cohesion Biosciences
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PARVG miRNA 3'UTR clone - MiUTR3H-09760 from Creative biogene
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PARVG miRNA 3'UTR clone - MiUTR3H-09761 from Creative biogene
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PARVG miRNA 3'UTR clone - MiUTR3H-09762 from Creative biogene
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