Gene Symbol | MTHFD2 |
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Entrez Gene | 10797 |
Alt Symbol | NMDMC |
Species | Human |
Gene Type | protein-coding |
Description | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
Other Description | NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase|bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial |
Swissprots | Q7Z650 Q53S36 Q53G90 P13995 Q53GV5 |
Accessions | AAX93061 EAW99670 EAW99671 EAW99672 EAW99673 P13995 AK130664 AK222826 BAD96546 AK223041 BAD96761 AK300035 BAG61846 AK302245 BAG63597 AK313138 BAG35957 AU125762 BC001548 AAH01548 BC015062 AAH15062 BC017054 AAH17054 BX475613 CB124593 DQ894679 ABM85605 X16396 CAA34431 XM_006711924 XP_006711987 NM_006636 NP_006627 NR_027405 NM_001040409 |
Subcellular Location | Mitochondrion. |
Top Pathways | One carbon pool by folate |
MTHFD2 CRISPR/Cas9 KO Plasmid (h) - sc-403474 from Santa Cruz Biotechnology
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MTHFD2 HDR Plasmid (h) - sc-403474-HDR from Santa Cruz Biotechnology
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MTHFD2 Double Nickase Plasmid (h) - sc-403474-NIC from Santa Cruz Biotechnology
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MTHFD2 Double Nickase Plasmid (h2) - sc-403474-NIC-2 from Santa Cruz Biotechnology
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MTHFD2 CRISPR Activation Plasmid (h) - sc-403474-ACT from Santa Cruz Biotechnology
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MTHFD2 CRISPR Activation Plasmid (h2) - sc-403474-ACT-2 from Santa Cruz Biotechnology
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MTHFD2 Lentiviral Activation Particles (h) - sc-403474-LAC from Santa Cruz Biotechnology
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MTHFD2 Lentiviral Activation Particles (h2) - sc-403474-LAC-2 from Santa Cruz Biotechnology
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MTHFD2 siRNA (h) - sc-75937 from Santa Cruz Biotechnology
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MTHFD2 shRNA Plasmid (h) - sc-75937-SH from Santa Cruz Biotechnology
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MTHFD2 shRNA (h) Lentiviral Particles - sc-75937-V from Santa Cruz Biotechnology
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MTHFD2 RNAi - H00010797-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112381 from Sigma-Aldrich
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MISSION® esiRNA - EHU099711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14706 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14706 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07677 from Sigma-Aldrich
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MTHFD2 siRNA (Human) - CRH7357 from Cohesion Biosciences
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shRNA set against Human MTHFD2 (NM_006636.3) - SHH346336 from Creative biogene
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shRNA set against Human MTHFD2(NM_006636.3) - SHH206201 from Creative biogene
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MTHFD2 shRNA Plasmid (Human) - CHH7357 from Cohesion Biosciences
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MTHFD2 miRNA 3'UTR clone - MiUTR1H-06507 from Creative biogene
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