Gene Symbol | MCUR1 |
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Entrez Gene | 63933 |
Alt Symbol | C6orf79, CCDC90A |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial calcium uniporter regulator 1 |
Other Description | coiled-coil domain containing 90A|coiled-coil domain-containing protein 90A, mitochondrial |
Swissprots | Q96AQ8 Q9H7F8 Q96JS7 |
Accessions | EAW55346 EAW55347 EAW55348 Q96AQ8 AI309194 AK024611 BAB14934 AK123750 BC008234 AAH08234 BC016850 AAH16850 BP382285 BX640678 DA892975 XM_011514802 XP_011513104 NM_022102 NM_001031713 NP_001026883 |
Function | Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake, possibly via a direct interaction with MCU. {ECO:0000269|PubMed:23178883}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:23178883}; Multi-pass membrane protein {ECO:0000269|PubMed:23178883}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:23178883}. |
CCDC90A CRISPR/Cas9 KO Plasmid (h) - sc-406721 from Santa Cruz Biotechnology
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CCDC90A HDR Plasmid (h) - sc-406721-HDR from Santa Cruz Biotechnology
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CCDC90A Double Nickase Plasmid (h) - sc-406721-NIC from Santa Cruz Biotechnology
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CCDC90A Double Nickase Plasmid (h2) - sc-406721-NIC-2 from Santa Cruz Biotechnology
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CCDC90A CRISPR Activation Plasmid (h) - sc-406721-ACT from Santa Cruz Biotechnology
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CCDC90A CRISPR Activation Plasmid (h2) - sc-406721-ACT-2 from Santa Cruz Biotechnology
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CCDC90A Lentiviral Activation Particles (h) - sc-406721-LAC from Santa Cruz Biotechnology
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CCDC90A Lentiviral Activation Particles (h2) - sc-406721-LAC-2 from Santa Cruz Biotechnology
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CCDC90A siRNA (h) - sc-95441 from Santa Cruz Biotechnology
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CCDC90A shRNA Plasmid (h) - sc-95441-SH from Santa Cruz Biotechnology
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CCDC90A shRNA (h) Lentiviral Particles - sc-95441-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5583 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5583 from Sigma-Aldrich
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MCUR1 siRNA (Human) - CRJ1871 from Cohesion Biosciences
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CCDC90A CRISPR/Cas9 KO Plasmid (h2) - sc-406721-KO-2 from Santa Cruz Biotechnology
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CCDC90A HDR Plasmid (h2) - sc-406721-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CCDC90A (NM_001031713.3) - SHH257309 from Creative biogene
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MCUR1 shRNA Plasmid (Human) - CHJ1871 from Cohesion Biosciences
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