Gene Symbol | APEH |
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Entrez Gene | 327 |
Alt Symbol | AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH |
Species | Human |
Gene Type | protein-coding |
Description | acylaminoacyl-peptide hydrolase |
Other Description | N-acylaminoacyl-peptide hydrolase|acyl-peptide hydrolase|acylamino-acid-releasing enzyme|acylaminoacyl-peptidase|oxidized protein hydrolase |
Swissprots | Q9P0Y2 P13798 Q9BQ33 |
Accessions | EAW64994 EAW64995 EAW64996 EAW64997 EAW64998 P13798 AF141383 AAF37321 AK314962 BC000362 AAH00362 BC001499 AAH01499 BC001826 AAH01826 D38441 BAA07476 DQ891418 ABM82344 DQ894592 ABM85518 S90797 S90805 XM_005265097 XP_005265154 XM_005265098 XP_005265155 XM_011533656 XP_011531958 XM_011533657 XP_011531959 XM_011533658 XP_011531960 XM_011533659 XP_011531961 XM_011533660 XP_011531962 XM_011533661 XP_011531963 XM_011533662 XP_011531964 XM_011533663 XP_011531965 NM_001640 NP_001631 |
Function | This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. {ECO:0000269|PubMed:1861871, ECO:0000269|PubMed:2006156}. |
Subcellular Location | Cytoplasm. |
APEH CRISPR/Cas9 KO Plasmid (h) - sc-408710 from Santa Cruz Biotechnology
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APEH HDR Plasmid (h) - sc-408710-HDR from Santa Cruz Biotechnology
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APEH Double Nickase Plasmid (h) - sc-408710-NIC from Santa Cruz Biotechnology
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APEH Double Nickase Plasmid (h2) - sc-408710-NIC-2 from Santa Cruz Biotechnology
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APEH CRISPR Activation Plasmid (h) - sc-408710-ACT from Santa Cruz Biotechnology
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APEH CRISPR Activation Plasmid (h2) - sc-408710-ACT-2 from Santa Cruz Biotechnology
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APEH Lentiviral Activation Particles (h) - sc-408710-LAC from Santa Cruz Biotechnology
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APEH Lentiviral Activation Particles (h2) - sc-408710-LAC-2 from Santa Cruz Biotechnology
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APEH siRNA (h) - sc-78303 from Santa Cruz Biotechnology
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APEH shRNA Plasmid (h) - sc-78303-SH from Santa Cruz Biotechnology
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APEH shRNA (h) Lentiviral Particles - sc-78303-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU052421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2008 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2008 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00143 from Sigma-Aldrich
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APEH siRNA (Human) - CRH0228 from Cohesion Biosciences
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APEH - MBS8239826 from MyBioSource
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shRNA set against Human APEH (NM_001640.3) - SHH238162 from Creative biogene
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shRNA set against Human APEH(NM_001640.3) - SHG064375 from Creative biogene
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Human APEH siRNA - orb260730 from Biorbyt
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APEH shRNA Plasmid (Human) - CHH0228 from Cohesion Biosciences
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APEH miRNA 3'UTR clone - MiUTR1H-00463 from Creative biogene
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