Numb

Gene Symbol Numb
Entrez Gene 18222
Alt Symbol Nb
Species Mouse
Gene Type protein-coding
Description numb gene homolog (Drosophila)
Other Description protein numb homolog
Swissprots Q9QZS3 Q9QZR1 Q9DC57 P70422 Q9QZS4 Q8CIB1
Accessions EDL02747 EDL02748 EDL02749 EDL02750 EDL02751 EDL02752 Q9QZS3 AF169191 AAD47834 AF169192 AAD47835 AF170709 AAD47836 AK004553 BAB23367 AK085841 AK164313 AK169548 BC033459 AAH33459 BC050108 AAH50108 BY129388 U70674 AAB09586 XM_006515572 XP_006515635 XM_006515573 XP_006515636 XM_006515574 XP_006515637 XM_006515575 XP_006515638 XM_006515576 XP_006515639 XM_006515577 XP_006515640 XM_006515578 XP_006515641 XM_011244012 XP_011242314 NM_001136075 NP_001129547 NM_001272055 NP_001258984 NM_001272056 NP_001258985 NM_010949 NP_035079 NR_073563 NR_073564
Function Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. {ECO:0000269|PubMed:10841580, ECO:0000269|PubMed:12410312, ECO:0000269|PubMed:15273690, ECO:0000269|PubMed:17174898}.
Subcellular Location Membrane; Peripheral membrane protein.
Tissue Specificity Expressed in subventricular zone (SVZ) neuroprogenitors and ependymal cells. {ECO:0000269|PubMed:17174898}.
Top Pathways Notch signaling pathway

Mouse Numb Homolog Protein - abx068375 from Abbexa

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Protein numb homolog(Numb) - CSB-YP882586MO CSB-EP882586MO CSB-BP882586MO CSB-MP882586MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse NUMB Protein - NUMB-10985M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

NUMB Recombinant Protein (OPCD05843) - OPCD05843 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Numb Homolog (NUMB), Recombinant Protein - MBS2018553 from MyBioSource

Category Protein
Prices $200.00, $430.00, $665.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Mouse

Protein numb homolog (Numb), Recombinant Protein - MBS1395335 from MyBioSource

Category Protein
Prices $1,455.00, $1,455.00, $1,680.00, $1,680.00, $2,470.00, $2,470.00, $2,910.00, $2,910.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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