| Gene Symbol |
ARHGAP6
|
| Entrez Gene |
395
|
| Alt Symbol |
RHOGAP6, RHOGAPX-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho GTPase activating protein 6
|
| Other Description |
Rho-type GTPase-activating protein RhoGAPX-1|rho GTPase-activating protein 6|rho-type GTPase-activating protein 6
|
| Swissprots |
Q9UK81 O43437 B2RWQ0 Q9UK82 O43182 Q9P1B3
|
| Accessions |
EAW98786 EAW98787 EAW98788 EAW98789 EAW98790 EAW98791 O43182 AB208792 BAD92029 AF012272 AAC98539 AF022212 AAC98540 AF117067 AAF43261 AF177663 AAD53166 AF177665 AAD55087 AK293078 BAF85767 AK297713 BAG60069 AK297747 BAG60097 AK303444 BAH13963 BC035785 BC150635 AAI50636 HY018118 NM_001287242 NP_001274171 NM_006125 NP_006116 NM_013423 NP_038267 NM_013427 NP_038286 NR_109776 NM_001174 NM_013422
|
| Function |
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology. {ECO:0000269|PubMed:10699171}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10699171}.
|
| Tissue Specificity |
Highly expressed in kidney, heart and skeletal muscle followed by retina, lymphoblast, placenta, lung, brain, pancreas and liver.
|