RARG
| Gene Symbol | RARG |
|---|---|
| Entrez Gene | 5916 |
| Alt Symbol | NR1B3, RARC |
| Species | Human |
| Gene Type | protein-coding |
| Description | retinoic acid receptor, gamma |
| Other Description | RAR-gamma|nuclear receptor subfamily 1 group B member 3|retinoic acid nuclear receptor gamma variant 1|retinoic acid nuclear receptor gamma variant 2|retinoic acid receptor gamma |
| Swissprots | Q15281 B7ZAE4 P22932 B7Z492 Q9UJ38 Q9H1I3 Q52LZ8 Q9BYX8 B7Z4F1 J3KNP6 P13631 |
| Accessions | AAG41594 AAG41595 CAA40548 CAB60726 CAM91171 EAW96676 EAW96677 EAW96678 P13631 AB307689 BAH02280 AK290588 BAF83277 AK297023 BAH12478 AK297110 BAH12500 AK297277 BAH12537 AK297801 BAH12670 AK301057 BAH13399 AK316259 BAH14630 AL701206 AW002722 BC019098 BC064524 BC072462 BC093727 AAH93727 BC093729 AAH93729 BC098421 CO394652 DA436501 DA552724 DC294855 HQ692828 ADZ17339 HQ692829 ADZ17340 L12060 M24857 AAA52692 M32074 AAA60253 M38258 AAA60254 M57707 AAA63254 XM_005269054 XP_005269111 XM_005269055 XP_005269112 XM_005269056 XP_005269113 XM_005269057 XP_005269114 XM_011538628 XP_011536930 NM_000966 NP_000957 NM_001042728 NP_001036193 NM_001243730 NP_001230659 NM_001243731 NP_001230660 NM_001243732 NP_001230661 |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus. |
RARγ CRISPR/Cas9 KO Plasmid (h) - sc-401152 from Santa Cruz Biotechnology
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RARγ HDR Plasmid (h) - sc-401152-HDR from Santa Cruz Biotechnology
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RARγ Double Nickase Plasmid (h) - sc-401152-NIC from Santa Cruz Biotechnology
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RARγ Double Nickase Plasmid (h2) - sc-401152-NIC-2 from Santa Cruz Biotechnology
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RARγ CRISPR Activation Plasmid (h) - sc-401152-ACT from Santa Cruz Biotechnology
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RARγ CRISPR Activation Plasmid (h2) - sc-401152-ACT-2 from Santa Cruz Biotechnology
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RARγ Lentiviral Activation Particles (h) - sc-401152-LAC from Santa Cruz Biotechnology
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RARγ Lentiviral Activation Particles (h2) - sc-401152-LAC-2 from Santa Cruz Biotechnology
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RARγ siRNA (h) - sc-36392 from Santa Cruz Biotechnology
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RARγ shRNA Plasmid (h) - sc-36392-SH from Santa Cruz Biotechnology
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RARγ shRNA (h) Lentiviral Particles - sc-36392-V from Santa Cruz Biotechnology
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RAR gamma/NR1B3 RNAi - H00005916-R01 from Novus Biologicals
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MISSION® esiRNA - EHU158191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17963 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17963 from Sigma-Aldrich
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RARG siRNA (Human) - CRH4002 from Cohesion Biosciences
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RARG - MBS8201576 from MyBioSource
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shRNA set against Human RARG (NM_000966.5) - SHH389784 from Creative biogene
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shRNA set against Human RARG(NM_001243731.1) - SHR165300 from Creative biogene
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shRNA set against Human RARG(NM_001243732.1) - SHR165318 from Creative biogene
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shRNA set against Human RARG(NM_001243730.1) - SHR165408 from Creative biogene
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Human RARG siRNA - orb264504 from Biorbyt
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RARG shRNA Plasmid (Human) - CHH4002 from Cohesion Biosciences
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RARG miRNA 3'UTR clone - MiUTR1H-08633 from Creative biogene
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RARG miRNA 3'UTR clone - MiUTR1H-08634 from Creative biogene
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