ELF2
| Gene Symbol | ELF2 |
|---|---|
| Entrez Gene | 1998 |
| Alt Symbol | EU32, NERF, NERF-1A, NERF-1B, NERF-1a,b, NERF-2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | E74-like factor 2 (ets domain transcription factor) |
| Other Description | ETS-related transcription factor Elf-2|ets family transcription factor ELF2C|new Ets-related factor |
| Swissprots | Q15724 Q6P1K5 Q15723 Q15725 E9PCX3 |
| Accessions | EAX05123 EAX05124 EAX05125 EAX05126 Q15723 AF256222 AAF67195 AF256223 AAF67196 AK301307 BAH13456 AK303782 BAH14050 AK311505 AK316455 BAH14826 BC034951 AAH34951 BC065025 AAH65025 BI770157 BQ221720 DQ359746 ABD15131 DQ890870 ABM81796 DQ894026 ABM84952 DR000047 LN626691 LN626692 U43188 AAB37759 U43189 AAB37760 XM_005262803 XP_005262860 XM_005262804 XP_005262861 XM_005262805 XP_005262862 XM_005262806 XP_005262863 XM_006714128 XP_006714191 XM_006714129 XP_006714192 XM_006714130 XP_006714193 XM_011531710 XP_011530012 XM_011531711 XP_011530013 XM_011531712 XP_011530014 XM_011531713 XP_011530015 XM_011531714 XP_011530016 NM_001276457 NP_001263386 NM_001276458 NP_001263387 NM_001276459 NP_001263388 NM_006874 NP_006865 NM_201999 NP_973728 |
| Function | Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes. {ECO:0000269|PubMed:8756667}. |
NERF CRISPR/Cas9 KO Plasmid (h) - sc-405891 from Santa Cruz Biotechnology
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NERF HDR Plasmid (h) - sc-405891-HDR from Santa Cruz Biotechnology
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NERF Double Nickase Plasmid (h) - sc-405891-NIC from Santa Cruz Biotechnology
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NERF Double Nickase Plasmid (h2) - sc-405891-NIC-2 from Santa Cruz Biotechnology
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NERF CRISPR Activation Plasmid (h) - sc-405891-ACT from Santa Cruz Biotechnology
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NERF CRISPR Activation Plasmid (h2) - sc-405891-ACT-2 from Santa Cruz Biotechnology
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NERF Lentiviral Activation Particles (h) - sc-405891-LAC from Santa Cruz Biotechnology
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NERF Lentiviral Activation Particles (h2) - sc-405891-LAC-2 from Santa Cruz Biotechnology
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NERF siRNA (h) - sc-43961 from Santa Cruz Biotechnology
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NERF shRNA Plasmid (h) - sc-43961-SH from Santa Cruz Biotechnology
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NERF shRNA (h) Lentiviral Particles - sc-43961-V from Santa Cruz Biotechnology
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ELF2 RNAi - H00001998-R01 from Novus Biologicals
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ELF2 RNAi - H00001998-R02 from Novus Biologicals
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MISSION® esiRNA - EHU113441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7800 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7800 from Sigma-Aldrich
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ELF2 siRNA (Human) - CRH1382 from Cohesion Biosciences
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ELF2 - MBS8221164 from MyBioSource
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NERF CRISPR/Cas9 KO Plasmid (h2) - sc-405891-KO-2 from Santa Cruz Biotechnology
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NERF HDR Plasmid (h2) - sc-405891-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ELF2 (NM_006874.2) - SHH285005 from Creative biogene
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shRNA set against Human ELF2(NM_201999.1) - SHH031133 from Creative biogene
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shRNA set against Human ELF2(NM_006874.2) - SHH031151 from Creative biogene
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Human ELF2 siRNA - orb261884 from Biorbyt
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ELF2 shRNA Plasmid (Human) - CHH1382 from Cohesion Biosciences
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