| Gene Symbol |
POU6F1
|
| Entrez Gene |
5463
|
| Alt Symbol |
BRN5, MPOU, TCFB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
POU class 6 homeobox 1
|
| Other Description |
POU domain, class 6, transcription factor 1|brain-5|brain-specific homeobox/POU domain protein 5|brn-5|mPOU homeobox protein
|
| Swissprots |
Q15944 Q6DK47 Q14863 Q7Z7P6
|
| Accessions |
EAW58179 EAW58180 Q14863 AI417271 AK095191 BAG53003 AL832881 AW445212 BC051326 AAH51326 BC074765 AAH74765 BC107090 AAI07091 BM703234 CK002954 DA026332 DA084199 EU446650 ABZ92179 L14482 Z21966 CAA79977 NM_002702 NP_002693 NR_026893
|
| Function |
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3'). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.
|
![Western Blot: POU6F1 Overexpression Lysate (Adult Normal) [NBP2-08080] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for POU6F1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14435_POU6F1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08080-img0001.jpg)