Gene Symbol | CEP97 |
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Entrez Gene | 79598 |
Alt Symbol | 2810403B08Rik, LRRIQ2 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 97kDa |
Other Description | centrosomal protein of 97 kDa|leucine-rich repeat and IQ domain-containing protein 2|leucine-rich repeats and IQ motif containing 2 |
Swissprots | B5MDY8 Q8NA71 Q8IW35 Q9H5T9 |
Accessions | EAW79777 EAW79778 Q8IW35 AK026700 BAB15531 AK093100 BAC04055 AK225573 AK294784 BAG57909 AK309806 AL833269 BC041085 AAH41085 DA520309 XM_006713743 XP_006713806 XM_011513125 XP_011511427 XM_011513126 XP_011511428 XM_011513127 XP_011511429 NM_001303401 NP_001290330 NM_024548 NP_078824 |
Function | Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. {ECO:0000269|PubMed:17719545}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17719545}. |
CEP97 CRISPR/Cas9 KO Plasmid (h) - sc-404653 from Santa Cruz Biotechnology
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CEP97 HDR Plasmid (h) - sc-404653-HDR from Santa Cruz Biotechnology
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CEP97 Double Nickase Plasmid (h) - sc-404653-NIC from Santa Cruz Biotechnology
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CEP97 Double Nickase Plasmid (h2) - sc-404653-NIC-2 from Santa Cruz Biotechnology
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CEP97 CRISPR Activation Plasmid (h) - sc-404653-ACT from Santa Cruz Biotechnology
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CEP97 CRISPR Activation Plasmid (h2) - sc-404653-ACT-2 from Santa Cruz Biotechnology
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CEP97 Lentiviral Activation Particles (h) - sc-404653-LAC from Santa Cruz Biotechnology
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CEP97 Lentiviral Activation Particles (h2) - sc-404653-LAC-2 from Santa Cruz Biotechnology
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CEP97 siRNA (h) - sc-78324 from Santa Cruz Biotechnology
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CEP97 shRNA Plasmid (h) - sc-78324-SH from Santa Cruz Biotechnology
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CEP97 shRNA (h) Lentiviral Particles - sc-78324-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5977 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5977 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10422 from Sigma-Aldrich
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CEP97 siRNA (Human) - CRJ2417 from Cohesion Biosciences
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CEP97 - MBS8238050 from MyBioSource
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shRNA set against Human CEP97 (NM_024548.2) - SHH262045 from Creative biogene
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Human CEP97 siRNA - orb272918 from Biorbyt
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CEP97 shRNA Plasmid (Human) - CHJ2417 from Cohesion Biosciences
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CEP97 miRNA 3'UTR clone - MiUTR1H-05929 from Creative biogene
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