Gene Symbol | STK39 |
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Entrez Gene | 27347 |
Alt Symbol | DCHT, PASK, SPAK |
Species | Human |
Gene Type | protein-coding |
Description | serine threonine kinase 39 |
Other Description | STE20/SPS1 homolog|STE20/SPS1-related proline-alanine-rich protein kinase|Ste20-like protein kinase|proline-alanine-rich STE20-related kinase|serine threonine kinase 39 (STE20/SPS1 homolog, yeast)|serine/threonine-protein kinase 39|small intestine SPAK-like kinase|ste-20-related kinase |
Swissprots | Q53SS1 Q53S90 X5D9C8 Q9UER4 Q9UEW8 O14774 Q53SL7 |
Accessions | AAY14897 AAY15003 AAY24032 ABG34553 EAX11304 Q9UEW8 AF017635 AAB70552 AF030403 AAD01901 AF099989 AAC72238 AK126343 BC146813 BC166614 AAI66614 BF516344 BX647113 KJ534948 AHW56588 KJ534949 AHW56589 KJ534950 AHW56590 KJ534951 AHW56591 KJ534999 AHW56639 KJ535059 AHW56698 XM_005246465 XP_005246522 XM_011510966 XP_011509268 XM_011510967 XP_011509269 XM_011510968 XP_011509270 NM_013233 NP_037365 |
Function | May act as a mediator of stress-activated signals. |
Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. Note=Nucleus when caspase-cleaved. {ECO:0000305}. |
Tissue Specificity | Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis. |
SPAK CRISPR/Cas9 KO Plasmid (h) - sc-404440 from Santa Cruz Biotechnology
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SPAK HDR Plasmid (h) - sc-404440-HDR from Santa Cruz Biotechnology
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SPAK Double Nickase Plasmid (h) - sc-404440-NIC from Santa Cruz Biotechnology
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SPAK Double Nickase Plasmid (h2) - sc-404440-NIC-2 from Santa Cruz Biotechnology
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SPAK CRISPR Activation Plasmid (h) - sc-404440-ACT from Santa Cruz Biotechnology
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SPAK CRISPR Activation Plasmid (h2) - sc-404440-ACT-2 from Santa Cruz Biotechnology
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SPAK Lentiviral Activation Particles (h) - sc-404440-LAC from Santa Cruz Biotechnology
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SPAK Lentiviral Activation Particles (h2) - sc-404440-LAC-2 from Santa Cruz Biotechnology
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SPAK siRNA (h) - sc-76547 from Santa Cruz Biotechnology
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SPAK shRNA Plasmid (h) - sc-76547-SH from Santa Cruz Biotechnology
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SPAK shRNA (h) Lentiviral Particles - sc-76547-V from Santa Cruz Biotechnology
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PASK RNAi - H00023178-R02 from Novus Biologicals
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STK39 RNAi - H00027347-R02 from Novus Biologicals
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MISSION® esiRNA - EHU045551 from Sigma-Aldrich
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MISSION® siRNA - SIHK2195 from Sigma-Aldrich
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MISSION® siRNA - SIHK2197 from Sigma-Aldrich
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MISSION® siRNA - SIHK2196 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20745 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20745 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09676 from Sigma-Aldrich
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STK39 siRNA (Human) - CRH9096 from Cohesion Biosciences
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STK39 - MBS8235531 from MyBioSource
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shRNA set against Human STK39 (NM_013233.2) - SHH419896 from Creative biogene
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shRNA set against Human STK39(NM_013233.2) - SHR089400 from Creative biogene
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STK39 shRNA Plasmid (Human) - CHH9096 from Cohesion Biosciences
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