Gene Symbol | Dffa |
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Entrez Gene | 13347 |
Alt Symbol | A330085O09Rik, DFF35, Dff45, ICAD, ICAD-L, ICAD-S |
Species | Mouse |
Gene Type | protein-coding |
Description | DNA fragmentation factor, alpha subunit |
Other Description | DNA fragmentation factor 45 kDa subunit|DNA fragmentation factor subunit alpha|inhibitor of CAD |
Swissprots | O54786 O54787 Q8BQC7 B2KFX0 |
Accessions | EDL14846 EDL14847 EDL14848 EDL14849 O54786 AA512775 AB009375 BAA24140 AB009376 BAA24141 AI116789 AI956986 AK039227 BAC30285 AK051011 BAC34496 AK079634 BAC37710 AK154488 BB183843 BC058213 AAH58213 BI736905 BU695917 BY170336 BY208552 BY244454 BY636093 NM_001025296 NP_001020467 NM_010044 NP_034174 NR_104263 |
Function | Inhibitor of the caspase-activated DNase (DFF40). |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | Apoptosis |
ICAD CRISPR/Cas9 KO Plasmid (m) - sc-419991 from Santa Cruz Biotechnology
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ICAD HDR Plasmid (m) - sc-419991-HDR from Santa Cruz Biotechnology
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ICAD Double Nickase Plasmid (m) - sc-419991-NIC from Santa Cruz Biotechnology
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ICAD Double Nickase Plasmid (m2) - sc-419991-NIC-2 from Santa Cruz Biotechnology
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ICAD CRISPR Activation Plasmid (m) - sc-419991-ACT from Santa Cruz Biotechnology
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ICAD CRISPR Activation Plasmid (m2) - sc-419991-ACT-2 from Santa Cruz Biotechnology
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ICAD Lentiviral Activation Particles (m) - sc-419991-LAC from Santa Cruz Biotechnology
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ICAD Lentiviral Activation Particles (m2) - sc-419991-LAC-2 from Santa Cruz Biotechnology
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ICAD siRNA (m) - sc-35625 from Santa Cruz Biotechnology
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ICAD shRNA Plasmid (m) - sc-35625-SH from Santa Cruz Biotechnology
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ICAD shRNA (m) Lentiviral Particles - sc-35625-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU059131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29932 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29932 from Sigma-Aldrich
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DFFA siRNA (Mouse) - CRM1019 from Cohesion Biosciences
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DFFA - MBS8215105 from MyBioSource
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shRNA set against Mouse DFFA (NM_010044.2) - SHH277281 from Creative biogene
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shRNA set against Mouse Dffa(NM_001025296.1) - SHH002135 from Creative biogene
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shRNA set against Mouse Dffa(NM_010044.2) - SHH002161 from Creative biogene
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shRNA set against Mouse Dffa(NM_001025296.1) - SHH002179 from Creative biogene
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DFFA shRNA Plasmid (Mouse) - CHM1019 from Cohesion Biosciences
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DFFA miRNA 3'UTR clone - MiUTR1M-03817 from Creative biogene
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DFFA miRNA 3'UTR clone - MiUTR1M-03818 from Creative biogene
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