Gene Symbol | ICAM2 |
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Entrez Gene | 3384 |
Alt Symbol | CD102 |
Species | Human |
Gene Type | protein-coding |
Description | intercellular adhesion molecule 2 |
Other Description | ICAM-2 |
Swissprots | Q14600 P13598 |
Accessions | AAA36035 AAF34580 CAY39145 CDM22291 EAW94216 EAW94217 EAW94218 EAW94219 EAW94220 P13598 AB209878 BAD93115 AF340052 AAQ14909 AF340053 AAQ14910 AK223219 BAD96939 AK293110 BAF85799 AK295382 BAH12052 AK309953 BC003097 AAH03097 BM695682 BX363874 CA841927 CR541812 CAG46611 CR541834 CAG46633 DQ891843 ABM82769 DQ895031 ABM85957 X15606 CAA33630 NM_000873 NP_000864 NM_001099786 NP_001093256 NM_001099787 NP_001093257 NM_001099788 NP_001093258 NM_001099789 NP_001093259 |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Natural killer cell mediated cytotoxicity, Cell adhesion molecules (CAMs) |
ICAM-2 CRISPR/Cas9 KO Plasmid (h) - sc-403029 from Santa Cruz Biotechnology
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ICAM-2 HDR Plasmid (h) - sc-403029-HDR from Santa Cruz Biotechnology
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ICAM-2 Double Nickase Plasmid (h) - sc-403029-NIC from Santa Cruz Biotechnology
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ICAM-2 Double Nickase Plasmid (h2) - sc-403029-NIC-2 from Santa Cruz Biotechnology
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ICAM-2 CRISPR Activation Plasmid (h) - sc-403029-ACT from Santa Cruz Biotechnology
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ICAM-2 CRISPR Activation Plasmid (h2) - sc-403029-ACT-2 from Santa Cruz Biotechnology
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ICAM-2 Lentiviral Activation Particles (h) - sc-403029-LAC from Santa Cruz Biotechnology
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ICAM-2 Lentiviral Activation Particles (h2) - sc-403029-LAC-2 from Santa Cruz Biotechnology
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ICAM-2 siRNA (h) - sc-35626 from Santa Cruz Biotechnology
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ICAM-2 shRNA Plasmid (h) - sc-35626-SH from Santa Cruz Biotechnology
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ICAM-2 shRNA (h) Lentiviral Particles - sc-35626-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU143871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10428 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10428 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01347 from Sigma-Aldrich
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ICAM2 siRNA (Human) - CRH2302 from Cohesion Biosciences
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ICAM2 - MBS8208351 from MyBioSource
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shRNA set against Human ICAM2 (NM_000873.3) - SHH316393 from Creative biogene
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shRNA set against Human ICAM2(NM_000873.3) - SHL134274 from Creative biogene
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Human ICAM2 siRNA - orb262804 from Biorbyt
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ICAM2 shRNA Plasmid (Human) - CHH2302 from Cohesion Biosciences
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ICAM2 miRNA 3'UTR clone - MiUTR1H-04779 from Creative biogene
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ICAM2 miRNA 3'UTR clone - MiUTR3H-01131 from Creative biogene
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ICAM2 miRNA 3'UTR clone - MiUTR3H-01132 from Creative biogene
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ICAM2 miRNA 3'UTR clone - MiUTR3H-01133 from Creative biogene
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