| Gene Symbol |
ABCF1
|
| Entrez Gene |
23
|
| Alt Symbol |
ABC27, ABC50
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP-binding cassette, sub-family F (GCN20), member 1
|
| Other Description |
ATP-binding cassette 50 (TNF-alpha stimulated)|ATP-binding cassette sub-family F member 1|TNF-alpha-stimulated ABC protein|TNFalpha-inducible ATP-binding protein
|
| Swissprots |
Q8NE71 Q69YP6 O14897 A2BF75
|
| Accessions |
BAB63325 BAC54928 BAE78612 BAF31263 CCO13667 EAX03300 EAX03301 EAX03302 Q8NE71 AB209564 BAD92801 AF027302 AAC70891 AK298061 BAG60354 AK307551 AL832430 CAH10648 BC016772 AAH16772 BC034488 AAH34488 BC112923 AAI12924 BI547952 BM556481 BU620927 DQ891255 ABM82181 DQ894817 ABM85743 U66677 NM_001025091 NP_001020262 NM_001090 NP_001081
|
| Function |
Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. {ECO:0000269|PubMed:19570978}.
|
| Subcellular Location |
Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:9790762}.
|
![Western Blot: ABCF1 Overexpression Lysate (Denatured) [H00000023-T01] - ABCF1 transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/29967_ABCF1-Overexpression-Lysate-(Denatured)-Western-Blot-H00000023-T01-img0005.jpg)
![Western Blot: ABCF1 Overexpression Lysate (Adult Normal) [NBP2-08649] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABCF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14913_ABCF1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08649-img0001.jpg)