Gene Symbol | MMP9 |
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Entrez Gene | 4318 |
Alt Symbol | CLG4B, GELB, MANDP2, MMP-9 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 9 |
Other Description | macrophage gelatinase|matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|matrix metalloproteinase-9|type V collagenase |
Swissprots | Q9UCL1 Q3LR70 P14780 Q8N725 Q9H4Z1 B2R7V9 Q9UDK2 Q9UCJ9 |
Accessions | AAD37404 AAM97934 ABA03169 BAA20967 CAC07541 EAW75776 P14780 AK298246 BAH12743 AK301446 BAH13483 AK302530 BAH13736 AK303080 BAH13895 AK311648 AK313137 BAG35956 AK316145 BAH14516 AW468235 BC006093 AAH06093 CN288579 DQ896791 ABM87790 EU176415 ABW03866 HQ874462 AEA49029 J05070 AAA51539 NM_004994 NP_004985 |
Function | May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. {ECO:0000269|PubMed:1480034}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
Tissue Specificity | Produced by normal alveolar macrophages and granulocytes. |
Top Pathways | Leukocyte transendothelial migration, Bladder cancer, TNF signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway |
Active human MMP 9/ Lipocalin Complex full length protein - ab134455 from Abcam
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Active human MMP9 /TIMP1 full length protein (complex) - ab134451 from Abcam
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Active human MMP9/ TIMP1/Lipocalin full length protein (complex) - ab134445 from Abcam
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Active human MMP9 full length protein (proenzyme) - ab157344 from Abcam
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Active human MMP9 full length protein - ab168863 from Abcam
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Human MMP9 full length protein - ab39308 from Abcam
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Human MMP9 full length protein - ab82955 from Abcam
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Human MMP9 full length protein - ab82957 from Abcam
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Human MMP9 full length protein - ab138786 from Abcam
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Human MMP9 peptide - ab73733 from Abcam
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Human MMP9 protein fragment - ab155704 from Abcam
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Human MMP9 protein fragment - ab82907 from Abcam
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Human MMP9 protein fragment - ab82938 from Abcam
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Human MMP9 protein fragment - ab63127 from Abcam
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MMP9 peptide - ab41067 from Abcam
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MMP9 peptide - ab41068 from Abcam
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MMP9 peptide - ab41069 from Abcam
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MMP9 peptide - ab41070 from Abcam
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Mouse MMP9 full length protein - ab39309 from Abcam
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Rabbit MMP9 full length protein - ab125814 from Abcam
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MMP9 / Gelatinase B Antibody Blocking Peptide - LS-E4296 from LifeSpan Bioscience
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MMP9 / Gelatinase B Antibody Blocking Peptide - LS-E8133 from LifeSpan Bioscience
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MMP9 / Gelatinase B Antibody Blocking Peptide - LS-E29661 from LifeSpan Bioscience
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MMP9 / Gelatinase B Antibody Blocking Peptide - LS-E29660 from LifeSpan Bioscience
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MMP-9 Recombinant Protein - H00004318-P01 from Novus Biologicals
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