| Gene Symbol |
BTBD7
|
| Entrez Gene |
55727
|
| Alt Symbol |
FUP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BTB (POZ) domain containing 7
|
| Other Description |
BTB/POZ domain-containing protein 7
|
| Swissprots |
Q9HAA4 Q69Z05 Q9NVM0 Q9P203 Q86TS0 A8K5V7 Q7Z308
|
| Accessions |
EAW81525 EAW81526 EAW81527 EAW81528 EAW81529 Q9P203 AB040958 BAA96049 AI452701 AK001510 BAA91730 AK021953 BAB13946 AK074354 AK091287 AK291422 BAF84111 AK303355 BAG64416 AL049394 CAH10736 BC047071 AAH47071 BC141850 AAI41851 BC167795 AAI67795 BX248762 CAD66569 BX538231 CAD98074 XM_011536939 XP_011535241 XM_011546648 XP_011544950 NM_001002860 NP_001002860 NM_001289133 NP_001276062 NM_018167 NP_060637
|
| Function |
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|