| Gene Symbol |
thrb
|
| Entrez Gene |
30607
|
| Alt Symbol |
NR1A2, TR-beta, TR[b]1, fj24f03, trb, wu:fj24f03
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
thyroid hormone receptor beta
|
| Other Description |
TRbeta1|nuclear receptor subfamily 1 group A member 2|thyroid hormone receptor beta 1|thyroid hormone receptor beta 2|thyroid hormone receptor beta-1
|
| Swissprots |
Q9PVE4 A3QJW1 O42560 Q90Y31 B3DIF2
|
| Accessions |
AAB68764 Q9PVE4 AB759513 BAN67994 AF109732 AAF14239 AF302242 AAL06722 AF322218 BC163106 AAI63106 BC163114 AAI63114 XM_005159501 XP_005159558 XM_005159502 XP_005159559 XM_005159505 XP_005159562 XM_009294151 XP_009292426 XM_009294152 XP_009292427 XM_009294153 XP_009292428 XM_009294154 XP_009292429 XM_009294155 XP_009292430 XM_009294156 XP_009292431 XM_009294157 XP_009292432 NM_131340 NP_571415
|
| Function |
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for the thyroid gland hormone triiodothyronine (T3). Transactivating activity is ligand-dependent, and is repressed in the absence of T3. {ECO:0000269|PubMed:10687864}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Widely expressed in a range of adult tissues including the brain, eye, fin, gill, intestine, liver, swim bladder and ovary. In the eye, expressed in the outer nuclear layer of the retina. {ECO:0000269|PubMed:10687864, ECO:0000269|PubMed:17997606}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|