| Gene Symbol |
SERPINI1
|
| Entrez Gene |
5274
|
| Alt Symbol |
PI12, neuroserpin
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serpin peptidase inhibitor, clade I (neuroserpin), member 1
|
| Other Description |
PI-12|neuroserpin|peptidase inhibitor 12|serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1|serpin I1
|
| Swissprots |
Q6AHZ4 A8K217 D3DNP1 Q99574
|
| Accessions |
AAG01089 CAJ44935 CBF57588 EAW78571 EAW78572 EAW78573 Q99574 AK290082 BAF82771 BC018043 AAH18043 BQ086144 CR627434 CAH10520 DA270615 DA359846 Z81326 CAB03626 NM_001122752 NP_001116224 NM_005025 NP_005016
|
| Function |
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Predominantly expressed in the brain.
|