| Gene Symbol |
KRT7
|
| Entrez Gene |
3855
|
| Alt Symbol |
CK7, K2C7, K7, SCL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin 7, type II
|
| Other Description |
CK-7|cytokeratin 7|cytokeratin-7|keratin, 55K type II cytoskeletal|keratin, simple epithelial type I, K7|keratin, type II cytoskeletal 7|keratin-7|sarcolectin|type II mesothelial keratin K7|type-II keratin Kb7
|
| Swissprots |
Q9Y3R7 Q9BUD8 Q92676 P08729
|
| Accessions |
AAN64035 CAA31695 EAW58240 EAW58241 P08729 AF509887 AAN64031 AJ238246 CAB41416 AK025881 AK128505 AK128848 BAG54741 AK129924 AK225498 BC002700 AAH02700 BC009521 AAH09521 BC042076 BC107082 AAI07083 BC107083 AAI07084 BE740515 BE744321 BU527162 DQ892996 ABM83922 DQ896244 ABM87243 X03212 CAA26956 Z36852 XM_011538325 XP_011536627 XR_944545 NM_005556 NP_005547
|
| Function |
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). {ECO:0000269|PubMed:10492017, ECO:0000269|PubMed:12072504}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:2459129}.
|
| Tissue Specificity |
Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. {ECO:0000269|PubMed:12359226, ECO:0000269|PubMed:2415537}.
|