Gene Symbol | FOSL2 |
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Entrez Gene | 2355 |
Alt Symbol | FRA2 |
Species | Human |
Gene Type | protein-coding |
Description | FOS-like antigen 2 |
Other Description | FRA-2|fos-related antigen 2 |
Swissprots | Q6FG46 B4DYV4 P15408 B3KP27 B2RD58 |
Accessions | AAY14908 AAY14909 EAX00537 EAX00538 EAX00539 EAX00540 P15408 AK026959 BAB15603 AK055579 BAG51539 AK302622 BAG63866 AK315415 BAG37805 BC008899 BC022791 AAH22791 BC085197 BM023443 BQ574214 BX647822 CR542262 CAG47058 DQ893428 ABM84354 DQ896743 ABM87742 X16706 CAA34678 XM_005264231 XP_005264288 XM_006711976 XP_006712039 XM_006711977 XP_006712040 NM_005253 NP_005244 |
Function | Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts. {ECO:0000250}. |
Subcellular Location | Nucleus. |
Top Pathways | Osteoclast differentiation |
Fra-2 CRISPR/Cas9 KO Plasmid (h) - sc-400250 from Santa Cruz Biotechnology
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Fra-2 HDR Plasmid (h) - sc-400250-HDR from Santa Cruz Biotechnology
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Fra-2 Double Nickase Plasmid (h) - sc-400250-NIC from Santa Cruz Biotechnology
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Fra-2 Double Nickase Plasmid (h2) - sc-400250-NIC-2 from Santa Cruz Biotechnology
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Fra-2 CRISPR Activation Plasmid (h) - sc-400250-ACT from Santa Cruz Biotechnology
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Fra-2 CRISPR Activation Plasmid (h2) - sc-400250-ACT-2 from Santa Cruz Biotechnology
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Fra-2 Lentiviral Activation Particles (h) - sc-400250-LAC from Santa Cruz Biotechnology
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Fra-2 Lentiviral Activation Particles (h2) - sc-400250-LAC-2 from Santa Cruz Biotechnology
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Fra-2 siRNA (h) - sc-35407 from Santa Cruz Biotechnology
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Fra-2 shRNA Plasmid (h) - sc-35407-SH from Santa Cruz Biotechnology
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Fra-2 shRNA (h) Lentiviral Particles - sc-35407-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU072911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8874 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8874 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11248 from Sigma-Aldrich
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FOSL2 siRNA (Human) - CRH1646 from Cohesion Biosciences
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FRA2 RNAi - H00002355-R01 from Novus Biologicals
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FOSL2 - MBS8222641 from MyBioSource
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shRNA set against Human FOSL2 (NM_005253.3) - SHH296349 from Creative biogene
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shRNA set against Human FOSL2(NM_005253.3) - SHH065603 from Creative biogene
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Human FOSL2 siRNA - orb262148 from Biorbyt
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FOSL2 shRNA Plasmid (Human) - CHH1646 from Cohesion Biosciences
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FOSL2 miRNA 3'UTR clone - MiUTR1H-03808 from Creative biogene
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