| Gene Symbol |
VOPP1
|
| Entrez Gene |
81552
|
| Alt Symbol |
ECOP, GASP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vesicular, overexpressed in cancer, prosurvival protein 1
|
| Other Description |
EGFR-coamplified and overexpressed protein|Glioblastoma-amplified secreted protein|hypothetical protein DKFZp564K0822|putative NF-kappa-B-activating protein 055N
|
| Swissprots |
Q96AW1 Q6FIE3 B0AZU1 B2RAT4 Q9H0W4 Q8NBN8 Q96RE5 B3KS72 C9JWR3
|
| Accessions |
EAL23811 EAW50969 EAW50970 EAW50971 EAW50972 Q96AW1 AB097004 BAC77357 AF395824 AAK82888 AK000539 AK075391 BAC11590 AK090825 AK092992 BAG52634 AK126848 AK225755 AK309288 AK314338 BAG36981 AK315882 BAF98773 AL136610 CAB66545 AM393121 CAL37999 BC016650 AAH16650 CN299440 CR533483 CAG38514 DA814621 HY073578 HY076549 XM_011515537 XP_011513839 XM_011515538 XP_011513840 XM_011515539 XP_011513841 XM_011515540 XP_011513842 XM_011515541 XP_011513843 XM_011515542 XP_011513844 XM_011515543 XP_011513845 XM_011515544 XP_011513846 XM_011515545 XP_011513847 XM_011515546 XP_011513848 NM_001284282 NP_001271211 NM_001284283 NP_001271212 NM_001284284 NP_001271213 NM_030796 NP_110423
|
| Function |
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. {ECO:0000269|PubMed:15735698}.
|
| Subcellular Location |
Cytoplasmic vesicle membrane {ECO:0000269|PubMed:20571887}; Single-pass type I membrane protein {ECO:0000269|PubMed:20571887}. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
|
| Tissue Specificity |
Widely expressed with highest levels in thymus and ovary. {ECO:0000269|PubMed:11916499}.
|
![Western Blot: VOPP1 Overexpression Lysate (Adult Normal) [NBL1-10101] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VOPP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8753_VOPP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10101-img0002.jpg)