Gene Symbol | P2RY11 |
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Entrez Gene | 5032 |
Alt Symbol | P2Y11 |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 11 |
Other Description | P2Y purinoceptor 11|purinergic receptor P2Y11 |
Swissprots | Q96G91 O43190 B2R8X9 Q9BYU4 |
Accessions | EAW84077 Q96G91 AA310412 AF498921 AAM18130 AJ298334 CAC29362 AK313550 BAG36326 AY449733 AAR18077 BC009877 BC073827 AAH73827 NM_002566 NP_002557 |
Function | Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highest expression in liver and spleen. {ECO:0000269|PubMed:11278528}. |
Top Pathways | Neuroactive ligand-receptor interaction |
P2Y11 CRISPR/Cas9 KO Plasmid (h) - sc-405745 from Santa Cruz Biotechnology
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P2Y11 HDR Plasmid (h) - sc-405745-HDR from Santa Cruz Biotechnology
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P2Y11 Double Nickase Plasmid (h) - sc-405745-NIC from Santa Cruz Biotechnology
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P2Y11 Double Nickase Plasmid (h2) - sc-405745-NIC-2 from Santa Cruz Biotechnology
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P2Y11 CRISPR Activation Plasmid (h) - sc-405745-ACT from Santa Cruz Biotechnology
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P2Y11 CRISPR Activation Plasmid (h2) - sc-405745-ACT-2 from Santa Cruz Biotechnology
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P2Y11 Lentiviral Activation Particles (h) - sc-405745-LAC from Santa Cruz Biotechnology
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P2Y11 Lentiviral Activation Particles (h2) - sc-405745-LAC-2 from Santa Cruz Biotechnology
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P2Y11 siRNA (h) - sc-76026 from Santa Cruz Biotechnology
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P2Y11 shRNA Plasmid (h) - sc-76026-SH from Santa Cruz Biotechnology
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P2Y11 shRNA (h) Lentiviral Particles - sc-76026-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN16232 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16232 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05057 from Sigma-Aldrich
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P2RY11 siRNA (Human) - CRH3345 from Cohesion Biosciences
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P2Y11/P2RY11 RNAi - H00005032-R02 from Novus Biologicals
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P2Y11 CRISPR/Cas9 KO Plasmid (h2) - sc-405745-KO-2 from Santa Cruz Biotechnology
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P2Y11 HDR Plasmid (h2) - sc-405745-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human P2RY11 (NM_002566.4) - SHH369548 from Creative biogene
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Human P2RY11 siRNA - orb263847 from Biorbyt
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P2RY11 shRNA Plasmid (Human) - CHH3345 from Cohesion Biosciences
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P2RY11 miRNA 3'UTR clone - MiUTR1H-07442 from Creative biogene
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