Gene Symbol | IFNGR2 |
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Entrez Gene | 3460 |
Alt Symbol | AF-1, IFGR2, IFNGT1, IMD28 |
Species | Human |
Gene Type | protein-coding |
Description | interferon gamma receptor 2 (interferon gamma transducer 1) |
Other Description | IFN-gamma receptor 2|IFN-gamma-R2|interferon gamma receptor 2|interferon gamma receptor accessory factor 1|interferon gamma receptor accessory factor-1|interferon gamma receptor beta chain|interferon gamma transducer 1 |
Swissprots | Q9BTL5 P38484 |
Accessions | AAC52066 AAT45458 CCF76939 EAX09834 EAX09835 P38484 AI824138 AK292246 BAF84935 AK314005 BAG36717 BC003624 AAH03624 BG391103 BQ008968 CB992729 DQ892320 ABM83246 DQ895522 ABM86448 EF173886 ABM53159 U05875 AAA16955 U05877 AAA16956 XM_005260969 XP_005261026 XM_011529553 XP_011527855 XM_011529554 XP_011527856 NM_005534 NP_005525 |
Function | Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Salmonella infection, Inflammatory bowel disease (IBD), Tuberculosis, Herpes simplex infection, Cytokine-cytokine receptor interaction |
IFN-γRβ siRNA (h) - sc-40094 from Santa Cruz Biotechnology
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IFN-γRβ shRNA Plasmid (h) - sc-40094-SH from Santa Cruz Biotechnology
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IFN-γRβ shRNA (h) Lentiviral Particles - sc-40094-V from Santa Cruz Biotechnology
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IFN-gamma R2 RNAi - H00003460-R02 from Novus Biologicals
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MISSION® esiRNA - EHU038341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10494 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10494 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05487 from Sigma-Aldrich
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IFNGR2 siRNA (Human) - CRH2346 from Cohesion Biosciences
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IFNGR2 - MBS8228100 from MyBioSource
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shRNA set against Human IFNGR2 (NM_005534.3) - SHH317189 from Creative biogene
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shRNA set against Human IFNGR2(NM_005534.3) - SHL167114 from Creative biogene
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Human IFNGR2 siRNA - orb262848 from Biorbyt
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IFNGR2 shRNA Plasmid (Human) - CHH2346 from Cohesion Biosciences
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IFNGR2 miRNA 3'UTR clone - MiUTR1H-04819 from Creative biogene
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