Gene Symbol |
Cyp2d4
|
Entrez Gene |
171522
|
Alt Symbol |
Cyp2d18, Cyp2d22, Cyp2d4v1, Cyp2d4v2, Cyp2d6
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
cytochrome P450, family 2, subfamily d, polypeptide 4
|
Other Description |
CYPIID18|CYPIID4|Cytochrome P450, subfamily IID4|P450 2D-29/2D-35|P450-CMF3|P450-DB4|cytochrome P450 2D-29|cytochrome P450 2D-35|cytochrome P450 2D4|cytochrome P450 2d18|cytochrome P450, family 2, subfamily d, polypeptide 22|cytochrome P450, subfamily 2D, polypeptide 6|cytochrome P450, subfamily IID, polypeptide 6|cytochrome P450-CMF3|cytochrome P450-DB4|debrisoquine 4-hydroxylase
|
Swissprots |
Q64680 Q566D3 P13108 O35107
|
Accessions |
CAA36271 EDM15651 P13108 Q64680 AB008425 BAA23125 BC093609 AAH93609 FQ211703 M22331 AAA41052 U48219 AAC52882 U48220 AAC52883 NM_138515 NP_612524
|
Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
Top Pathways |
Steroid hormone biosynthesis
|