Gene Symbol | ABCC5 |
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Entrez Gene | 10057 |
Alt Symbol | ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
Other Description | ATP-binding cassette sub-family C member 5|canalicular multispecific organic anion transporter C|multi-specific organic anion transporter C|multidrug resistance-associated protein 5 |
Swissprots | Q9UQC3 O14517 Q86UX3 Q86W30 Q29ZA9 Q9UN85 B9EIQ2 O15440 Q9UNP5 Q29ZB1 |
Accessions | EAW78306 EAW78307 EAW78308 EAW78309 EAW78310 O15440 AB005659 BAA22887 AB019002 BAA76608 AB209103 BAD92340 AB209454 BAD92691 AF104942 AAD04169 AF146074 AAD37716 AK090667 AL359600 AL524917 AW207515 AY196484 AAO49801 AY754874 AAW82948 AY754875 AAW82949 AY754876 AAW82950 BC015334 AAH15334 BC050744 AAH50744 BC051358 BC140771 AAI40772 BC142670 AAI42671 BC142719 AAI42720 BC144495 BE085682 BX647245 BX649032 CN410200 CN429416 U66687 U83661 AAB71758 XM_005247058 XP_005247115 XM_005247059 XP_005247116 XM_011512314 XP_011510616 XM_011512315 XP_011510617 XM_011512316 XP_011510618 NM_001023587 NP_001018881 NM_005688 NP_005679 |
Function | Acts as a multispecific organic anion pump which can transport nucleotide analogs. {ECO:0000269|PubMed:10840050}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | All isoforms are equally expressed in retina. {ECO:0000269|PubMed:17521428}. |
Top Pathways | ABC transporters |
MRP5 CRISPR/Cas9 KO Plasmid (h) - sc-402443 from Santa Cruz Biotechnology
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MRP5 HDR Plasmid (h) - sc-402443-HDR from Santa Cruz Biotechnology
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MRP5 Double Nickase Plasmid (h) - sc-402443-NIC from Santa Cruz Biotechnology
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MRP5 Double Nickase Plasmid (h2) - sc-402443-NIC-2 from Santa Cruz Biotechnology
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MRP5 CRISPR Activation Plasmid (h) - sc-402443-ACT from Santa Cruz Biotechnology
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MRP5 CRISPR Activation Plasmid (h2) - sc-402443-ACT-2 from Santa Cruz Biotechnology
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MRP5 Lentiviral Activation Particles (h) - sc-402443-LAC from Santa Cruz Biotechnology
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MRP5 Lentiviral Activation Particles (h2) - sc-402443-LAC-2 from Santa Cruz Biotechnology
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MRP5 siRNA (h) - sc-35965 from Santa Cruz Biotechnology
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MRP5 shRNA Plasmid (h) - sc-35965-SH from Santa Cruz Biotechnology
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MRP5 shRNA (h) Lentiviral Particles - sc-35965-V from Santa Cruz Biotechnology
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ABCC5 RNAi - H00010057-R03 from Novus Biologicals
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MISSION® esiRNA - EHU134161 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09178 from Sigma-Aldrich
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ABCC5 siRNA (Human) - CRH6773 from Cohesion Biosciences
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ABCC5 RNAi - H00010057-R04 from Novus Biologicals
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ABCC5 - MBS8230316 from MyBioSource
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MRP5 CRISPR/Cas9 KO Plasmid (h2) - sc-402443-KO-2 from Santa Cruz Biotechnology
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MRP5 HDR Plasmid (h2) - sc-402443-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ABCC5 (NM_005688.2) - SHH229150 from Creative biogene
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shRNA set against Human ABCC5(NM_005688.2) - SHG024211 from Creative biogene
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shRNA set against Human ABCC5(NM_001023587.1) - SHG024247 from Creative biogene
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Human ABCC5 siRNA - orb267275 from Biorbyt
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ABCC5 shRNA Plasmid (Human) - CHH6773 from Cohesion Biosciences
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ABCC5 miRNA 3'UTR clone - MiUTR1H-00042 from Creative biogene
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