| Gene Symbol |
BAALC
|
| Entrez Gene |
79870
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
brain and acute leukemia, cytoplasmic
|
| Other Description |
brain and acute leukemia cytoplasmic protein
|
| Swissprots |
Q8WXS1 Q8WTP6 Q8WXS2 Q9HA93 Q8WXS0 Q8WXS3
|
| Accessions |
AAL50377 AAL50378 AAL50379 AAL50380 AAL50381 AAL50382 EAW91862 EAW91863 EAW91864 EAW91865 Q8WXS3 AF371319 AAL50515 AF371323 AAL50519 AK022077 BAB13960 AK093819 AK310816 BC011517 AAH11517 BC014365 BC035038 AAH35038 BI548687 DQ893318 ABM84244 DQ896633 ABM87632 NM_001024372 NP_001019543 NM_024812 NP_079088
|
| Function |
May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11707601}. Membrane {ECO:0000269|PubMed:11707601}. Note=Postsynaptic lipid rafts. {ECO:0000250}.
|
| Tissue Specificity |
Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm- derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin. {ECO:0000269|PubMed:11707601}.
|
![Western Blot: BAALC Overexpression Lysate (Adult Normal) [NBL1-07894] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BAALC.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9212_BAALC%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07894-img0002.jpg)