| Gene Symbol |
KRTDAP
|
| Entrez Gene |
388533
|
| Alt Symbol |
KDAP, UNQ467
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratinocyte differentiation-associated protein
|
| Other Description |
KIPV467
|
| Swissprots |
A1L4D7 P60985
|
| Accessions |
P60985 AI184682 AJ293408 AM392574 CAL37452 AM392667 CAL37545 AM392672 CAL37550 AM392738 CAL37616 AM392847 CAL37725 AM392851 CAL37729 AM393397 CAL38275 AM393477 CAL38354 AY359007 AAQ89366 BC130501 AAI30502 HQ258707 ADR83458 W95920 NM_001244847 NP_001231776 NM_207392 NP_997275
|
| Function |
May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis. {ECO:0000269|PubMed:15140226}.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:15140226}.
|
| Tissue Specificity |
Highly expressed in skin and detected at lower levels in thymus. In skin, found exclusively in lamellar granules of granular keratinocytes and in the intracellular space of the stratum corneum. Also highly expressed in oral mucosa, tongue, esophagus, and stomach, and at much lower levels in bladder and uterus. Not detected in gastrointestinal mucosa. {ECO:0000269|PubMed:15140226}.
|