Gene Symbol |
SYBU
|
Entrez Gene |
55638
|
Alt Symbol |
GOLSYN, OCSYN, SNPHL
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
syntabulin (syntaxin-interacting)
|
Other Description |
GOLSYN A protein|GOLSYN B protein|GOLSYN C protein|Golgi-localized protein|golgi-localized syntaphilin-related protein|implicated in syntaxin trafficking in neurons|microtubule-associated protein|syntabulin|syntaxin-1-binding protein
|
Swissprots |
Q5R1T2 Q8TCR6 Q8ND49 Q5R1T3 Q5Y2M6 Q9P256 B3KQX3 B3KU61 Q96D80 Q9NX95 A8K354 Q5R1T1
|
Accessions |
EAW91935 EAW91936 EAW91937 Q9NX95 AB040905 BAA95996 AB195676 BAD72976 AB195677 BAD72977 AB195678 BAD72978 AB195679 BAD72979 AK000373 BAA91121 AK055246 AK090559 BAG52185 AK091374 BAG52343 AK096558 BAG53323 AK290469 BAF83158 AK297182 BAH12518 AL713645 CAD28457 AL834406 CAD39068 AY705385 AAU93914 BC012082 AAH12082 BG702715 BU607867 CA395128 DA155137 DA530258 DA773983 DA787454 DA803330 DB127917 DB155885 DC350594 DN993094 XM_005250999 XP_005251056 XM_005251000 XP_005251057 XM_011517154 XP_011515456 NM_001099743 NP_001093213 NM_001099744 NP_001093214 NM_001099745 NP_001093215 NM_001099746 NP_001093216 NM_001099747 NP_001093217 NM_001099748 NP_001093218 NM_001099749 NP_001093219 NM_001099750 NP_001093220 NM_001099751 NP_001093221 NM_001099752 NP_001093222 NM_001099753 NP_001093223 NM_001099754 NP_001093224 NM_001099755 NP_001093225 NM_001099756 NP_001093226 NM_017786 NP_060256
|
Function |
Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development. {ECO:0000250}.
|
Subcellular Location |
Isoform 4: Golgi apparatus membrane; Single- pass membrane protein.
|
Tissue Specificity |
Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine. {ECO:0000269|PubMed:15656992}.
|