Gene Symbol | SPTA1 |
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Entrez Gene | 6708 |
Alt Symbol | EL2, HPP, HS3, SPH3, SPTA |
Species | Human |
Gene Type | protein-coding |
Description | spectrin, alpha, erythrocytic 1 |
Other Description | alpha-I spectrin|elliptocytosis 2|erythroid alpha-spectrin|spectrin alpha chain, erythrocyte|spectrin alpha chain, erythrocytic 1|spectrin, alpha, erythrocytic 1 (elliptocytosis 2) |
Swissprots | Q6LDY5 Q15514 P02549 Q5VYL2 Q5VYL1 |
Accessions | AAA53103 AAA60575 AAA60994 CCQ43201 EAW52816 EAW52817 EAW52818 EAW52819 P02549 AF060556 AAC15757 BC156496 AAI56497 BC172497 AAI72497 BU665064 CD616351 M11049 AAA60569 M61877 AAA60577 XM_011509916 XP_011508218 XM_011509917 XP_011508219 XM_011509918 XP_011508220 XM_011509919 XP_011508221 XR_921911 XR_921912 NM_003126 NP_003117 |
Function | Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. |
Subcellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. |
spectrin α I CRISPR/Cas9 KO Plasmid (h) - sc-403563 from Santa Cruz Biotechnology
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spectrin α I HDR Plasmid (h) - sc-403563-HDR from Santa Cruz Biotechnology
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spectrin α I Double Nickase Plasmid (h) - sc-403563-NIC from Santa Cruz Biotechnology
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spectrin α I Double Nickase Plasmid (h2) - sc-403563-NIC-2 from Santa Cruz Biotechnology
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spectrin α I CRISPR Activation Plasmid (h) - sc-403563-ACT from Santa Cruz Biotechnology
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spectrin α I CRISPR Activation Plasmid (h2) - sc-403563-ACT-2 from Santa Cruz Biotechnology
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spectrin α I Lentiviral Activation Particles (h) - sc-403563-LAC from Santa Cruz Biotechnology
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spectrin α I Lentiviral Activation Particles (h2) - sc-403563-LAC-2 from Santa Cruz Biotechnology
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spectrin α I siRNA (h) - sc-43430 from Santa Cruz Biotechnology
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spectrin α I shRNA Plasmid (h) - sc-43430-SH from Santa Cruz Biotechnology
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spectrin α I shRNA (h) Lentiviral Particles - sc-43430-V from Santa Cruz Biotechnology
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Spectrin alpha 1 RNAi - H00006708-R01 from Novus Biologicals
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MISSION® esiRNA - EHU056051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20539 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20539 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04353 from Sigma-Aldrich
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SPTA1 siRNA (Human) - CRH4577 from Cohesion Biosciences
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SPTA1 - MBS8227259 from MyBioSource
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spectrin α I CRISPR/Cas9 KO Plasmid (h2) - sc-403563-KO-2 from Santa Cruz Biotechnology
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spectrin α I HDR Plasmid (h2) - sc-403563-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SPTA1 (NM_003126.2) - SHH417480 from Creative biogene
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SPTA1 shRNA Plasmid (Human) - CHH4577 from Cohesion Biosciences
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SPTA1 miRNA 3'UTR clone - MiUTR1H-09883 from Creative biogene
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