| Gene Symbol | RAB34 |
|---|---|
| Entrez Gene | 83871 |
| Alt Symbol | RAB39, RAH |
| Species | Human |
| Gene Type | protein-coding |
| Description | RAB34, member RAS oncogene family |
| Other Description | ras-related protein Rab-34|ras-related protein Rab-39|ras-related protein Rah |
| Swissprots | E9PEJ9 Q96AR4 Q9BZG1 Q8NCJ8 B4E3A0 Q5BJE6 |
| Accessions | CAF86756 EAW51127 EAW51128 EAW51129 EAW51130 Q9BZG1 AF322067 AAK09397 AF327350 AAL05587 AJ277106 CAC81760 AK027312 BAB55034 AK074689 BAC11141 AK297850 BAG60182 AK304633 BAG65412 BC016841 AAH16841 BC066904 AAH66904 BC091510 AAH91510 BG251677 BG749591 BI523728 BT006702 AAP35348 CB111417 CB127976 CB136913 CX788239 DA070520 DQ890590 ABM92207 DQ893756 ABM84682 NM_001142624 NP_001136096 NM_001142625 NP_001136097 NM_001144942 NP_001138414 NM_001144943 NP_001138415 NM_001256276 NP_001243205 NM_001256277 NP_001243206 NM_001256278 NP_001243207 NM_031934 NP_114140 |
| Function | Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. {ECO:0000250, ECO:0000269|PubMed:21255211}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:21255211}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. |
Rab 34 CRISPR/Cas9 KO Plasmid (h) - sc-406606 from Santa Cruz Biotechnology
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Rab 34 HDR Plasmid (h) - sc-406606-HDR from Santa Cruz Biotechnology
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Rab 34 Double Nickase Plasmid (h) - sc-406606-NIC from Santa Cruz Biotechnology
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Rab 34 Double Nickase Plasmid (h2) - sc-406606-NIC-2 from Santa Cruz Biotechnology
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Rab 34 CRISPR Activation Plasmid (h) - sc-406606-ACT from Santa Cruz Biotechnology
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Rab 34 CRISPR Activation Plasmid (h2) - sc-406606-ACT-2 from Santa Cruz Biotechnology
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Rab 34 Lentiviral Activation Particles (h) - sc-406606-LAC from Santa Cruz Biotechnology
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Rab 34 Lentiviral Activation Particles (h2) - sc-406606-LAC-2 from Santa Cruz Biotechnology
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Rab 34 siRNA (h) - sc-45812 from Santa Cruz Biotechnology
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Rab 34 shRNA Plasmid (h) - sc-45812-SH from Santa Cruz Biotechnology
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Rab 34 shRNA (h) Lentiviral Particles - sc-45812-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17835 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17835 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02765 from Sigma-Aldrich
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RAB34 siRNA (Human) - CRJ3212 from Cohesion Biosciences
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RAB34 - MBS8230253 from MyBioSource
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shRNA set against Human RAB34 (NM_031934.5) - SHH388220 from Creative biogene
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Rab 34 CRISPR/Cas9 KO Plasmid (h2) - sc-406606-KO-2 from Santa Cruz Biotechnology
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Rab 34 HDR Plasmid (h2) - sc-406606-HDR-2 from Santa Cruz Biotechnology
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Human RAB34 siRNA - orb273713 from Biorbyt
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RAB34 shRNA Plasmid (Human) - CHJ3212 from Cohesion Biosciences
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RAB34 miRNA 3'UTR clone - MiUTR3H-11547 from Creative biogene
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RAB34 miRNA 3'UTR clone - MiUTR3H-11548 from Creative biogene
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RAB34 miRNA 3'UTR clone - MiUTR3H-11549 from Creative biogene
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