Gene Symbol | LMO2 |
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Entrez Gene | 4005 |
Alt Symbol | RBTN2, RBTNL1, RHOM2, TTG2 |
Species | Human |
Gene Type | protein-coding |
Description | LIM domain only 2 (rhombotin-like 1) |
Other Description | LIM domain only protein 2|LMO-2|T-cell translocation gene 2|T-cell translocation protein 2|cysteine-rich protein TTG-2|rhombotin 2|rhombotin-2|rhombotin-like 1 |
Swissprots | Q9HD58 P25791 |
Accessions | CDL93511 EAW68181 EAW68182 P25791 AF257211 AAF98804 AK127915 BC034041 AAH34041 BC035607 AAH35607 BC042426 AAH42426 BC073973 AAH73973 BM690599 BM699014 CN355348 DQ892333 ABM83259 DQ895538 ABM86464 X61118 CAA43430 XM_005252921 XP_005252978 XM_011520101 XP_011518403 NM_001142315 NP_001135787 NM_001142316 NP_001135788 NM_005574 NP_005565 |
Function | Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Transcriptional misregulation in cancer |
LMO2 CRISPR/Cas9 KO Plasmid (h) - sc-402169 from Santa Cruz Biotechnology
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LMO2 HDR Plasmid (h) - sc-402169-HDR from Santa Cruz Biotechnology
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LMO2 Double Nickase Plasmid (h) - sc-402169-NIC from Santa Cruz Biotechnology
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LMO2 Double Nickase Plasmid (h2) - sc-402169-NIC-2 from Santa Cruz Biotechnology
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LMO2 CRISPR Activation Plasmid (h) - sc-402169-ACT from Santa Cruz Biotechnology
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LMO2 CRISPR Activation Plasmid (h2) - sc-402169-ACT-2 from Santa Cruz Biotechnology
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LMO2 Lentiviral Activation Particles (h) - sc-402169-LAC from Santa Cruz Biotechnology
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LMO2 Lentiviral Activation Particles (h2) - sc-402169-LAC-2 from Santa Cruz Biotechnology
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LMO2 siRNA (h) - sc-38027 from Santa Cruz Biotechnology
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LMO2 shRNA Plasmid (h) - sc-38027-SH from Santa Cruz Biotechnology
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LMO2 shRNA (h) Lentiviral Particles - sc-38027-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11775 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11775 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06351 from Sigma-Aldrich
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LMO2 siRNA (Human) - CRH2711 from Cohesion Biosciences
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LMO2 RNAi - H00004005-R01 from Novus Biologicals
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shRNA set against Human LMO2 (NM_005574.3) - SHH331051 from Creative biogene
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Human LMO2 siRNA - orb263213 from Biorbyt
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LMO2 shRNA Plasmid (Human) - CHH2711 from Cohesion Biosciences
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LMO2 miRNA 3'UTR clone - MiUTR3H-02040 from Creative biogene
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LMO2 miRNA 3'UTR clone - MiUTR3H-02041 from Creative biogene
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LMO2 miRNA 3'UTR clone - MiUTR3H-02042 from Creative biogene
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