Gene Symbol | FGF4 |
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Entrez Gene | 2249 |
Alt Symbol | HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 4 |
Other Description | FGF-4|HSTF-1|fibroblast growth factor 4 splice isoform|heparin secretory transforming protein 1|heparin secretory-transforming protein 1|heparin-binding growth factor 4|human stomach cancer, transforming factor from FGF-related oncogene|kaposi sarcoma oncogene|oncogene HST|transforming protein KS3 |
Swissprots | P08620 B7U994 |
Accessions | AAB21430 AAB59555 AAB59556 CAF86234 EAW74752 P08620 AW340506 BC156333 AAI56334 BC172495 AAI72495 CN429959 FJ456981 ACJ68447 M17446 AAA59473 XM_005273847 XP_005273904 XM_006718475 XP_006718538 NM_002007 NP_001998 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. {ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-4 CRISPR/Cas9 KO Plasmid (h) - sc-403042 from Santa Cruz Biotechnology
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FGF-4 HDR Plasmid (h) - sc-403042-HDR from Santa Cruz Biotechnology
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FGF-4 Double Nickase Plasmid (h) - sc-403042-NIC from Santa Cruz Biotechnology
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FGF-4 Double Nickase Plasmid (h2) - sc-403042-NIC-2 from Santa Cruz Biotechnology
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FGF-4 CRISPR Activation Plasmid (h) - sc-403042-ACT from Santa Cruz Biotechnology
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FGF-4 CRISPR Activation Plasmid (h2) - sc-403042-ACT-2 from Santa Cruz Biotechnology
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FGF-4 Lentiviral Activation Particles (h) - sc-403042-LAC from Santa Cruz Biotechnology
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FGF-4 Lentiviral Activation Particles (h2) - sc-403042-LAC-2 from Santa Cruz Biotechnology
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FGF-4 siRNA (h) - sc-39450 from Santa Cruz Biotechnology
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FGF-4 shRNA Plasmid (h) - sc-39450-SH from Santa Cruz Biotechnology
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FGF-4 shRNA (h) Lentiviral Particles - sc-39450-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8661 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02309 from Sigma-Aldrich
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FGF4 siRNA (Human) - CRH1569 from Cohesion Biosciences
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FGF4 - MBS829501 from MyBioSource
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shRNA set against Human Fgf4 (NM_002007.2) - SHH294553 from Creative biogene
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Human FGF4 siRNA - orb262071 from Biorbyt
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FGF4 shRNA Plasmid (Human) - CHH1569 from Cohesion Biosciences
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FGF4 miRNA 3'UTR clone - MiUTR4H-TG03531 from Creative biogene
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