Gene Symbol | SEP15 |
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Entrez Gene | 9403 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | 15 kDa selenoprotein |
Other Description | - |
Swissprots | Q9GZW0 Q4GZG7 Q9NR01 O60613 Q9BS64 Q8WU00 |
Accessions | AAF78966 AAG31557 EAW73176 EAW73177 EAW73178 EAW73179 EAW73180 O60613 AF051894 AAC15478 AF288991 AAG31556 AK225252 AK225640 AL833575 CAJ18323 BC005294 AAH05294 BC016359 AAH16359 BC021697 AAH21697 BQ429619 BU941543 CB066894 NM_004261 NP_004252 NM_203341 NP_976086 |
Function | May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:11278576}. Note=The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum. |
Tissue Specificity | Higher levels in prostate and thyroid gland. {ECO:0000269|PubMed:9535873}. |
SEP15 CRISPR/Cas9 KO Plasmid (h) - sc-409741 from Santa Cruz Biotechnology
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SEP15 HDR Plasmid (h) - sc-409741-HDR from Santa Cruz Biotechnology
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SEP15 Double Nickase Plasmid (h) - sc-409741-NIC from Santa Cruz Biotechnology
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SEP15 Double Nickase Plasmid (h2) - sc-409741-NIC-2 from Santa Cruz Biotechnology
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SEP15 CRISPR Activation Plasmid (h) - sc-409741-ACT from Santa Cruz Biotechnology
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SEP15 CRISPR Activation Plasmid (h2) - sc-409741-ACT-2 from Santa Cruz Biotechnology
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SEP15 Lentiviral Activation Particles (h) - sc-409741-LAC from Santa Cruz Biotechnology
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SEP15 Lentiviral Activation Particles (h2) - sc-409741-LAC-2 from Santa Cruz Biotechnology
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SEP15 siRNA (h) - sc-88552 from Santa Cruz Biotechnology
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SEP15 shRNA Plasmid (h) - sc-88552-SH from Santa Cruz Biotechnology
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SEP15 shRNA (h) Lentiviral Particles - sc-88552-V from Santa Cruz Biotechnology
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SEP15 RNAi - H00009403-R01 from Novus Biologicals
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MISSION® esiRNA - EHU085871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19092 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19092 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07769 from Sigma-Aldrich
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SEPT15 siRNA (Human) - CRH6233 from Cohesion Biosciences
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SEP15 RNAi - H00009403-R02 from Novus Biologicals
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SEPT15 - MBS8207172 from MyBioSource
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shRNA set against Human Sep15 (NM_004261.3) - SHH404540 from Creative biogene
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shRNA set against Human SEP15(NM_004261.3) - SHR215022 from Creative biogene
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shRNA set against Human SEP15(NM_203341.1) - SHR215076 from Creative biogene
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Human SEPT15 siRNA - orb266735 from Biorbyt
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SEPT15 shRNA Plasmid (Human) - CHH6233 from Cohesion Biosciences
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SEP15 miRNA 3'UTR clone - MiUTR1H-09268 from Creative biogene
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