Gene Symbol |
Plcb4
|
Entrez Gene |
25031
|
Alt Symbol |
Beta4aa, RATBETA4AA
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
phospholipase C, beta 4
|
Other Description |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4|PLC-beta-4|phosphoinositide phospholipase C|phosphoinositide phospholipase C-beta-4|phospholipase C-beta-4
|
Swissprots |
Q9Z0G6 O88356 Q9QW07
|
Accessions |
EDL80292 EDL80293 EDL80295 EDL80296 Q9QW07 AF027571 AAC24984 AF031370 AAC98145 L15556 AAK13557 L18962 U57836 AAD10403 XM_006235083 XP_006235145 XM_006235085 XP_006235147 XM_006235088 XP_006235150 XM_006235089 XP_006235151 XM_006235094 XP_006235156 XM_008762248 XP_008760470 XM_008762249 XP_008760471 XM_008762250 XP_008760472 XM_008762251 XP_008760473 NM_024353 NP_077329
|
Function |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.
|
Tissue Specificity |
Preferentially expressed in the retina.
|
Top Pathways |
Oxytocin signaling pathway, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Adrenergic signaling in cardiomyocytes, Inflammatory mediator regulation of TRP channels
|