| Gene Symbol |
SYT5
|
| Entrez Gene |
6861
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptotagmin V
|
| Other Description |
synaptotagmin 5|synaptotagmin-5|sytV
|
| Swissprots |
B3KWJ8 Q86X72 O00445 B7Z300
|
| Accessions |
CAA65579 EAW72345 EAW72346 EAW72347 O00445 AK125182 BAG54160 AK295337 BAH12036 AK313067 BC029962 BC033683 AAH33683 BC046157 AAH46157 BM311004 BQ417474 DA529870 DB170891 DQ090951 AAY99640 Y19236 XM_006723339 XP_006723402 XM_006723340 XP_006723403 XM_006723341 XP_006723404 NM_001297774 NP_001284703 NM_003180 NP_003171
|
| Function |
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)- dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Recycling endosome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=In mast cells, localizes to the endocytic recycling compartment. {ECO:0000250}.
|
![Western Blot: Synaptotagmin 5 Overexpression Lysate (Adult Normal) [NBL1-16653] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Synaptotagmin 5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2895_Synaptotagmin%25205%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16653-img0002.jpg)