MAP3K14

Gene Symbol MAP3K14
Entrez Gene 9020
Alt Symbol FTDCR1B, HS, HSNIK, NIK
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase kinase 14
Other Description NF-kappa-beta-inducing kinase|serine/threonine-protein kinase NIK
Swissprots D3DX67 A8K2D8 Q8IYN1 Q99558
Accessions ABC40733 EAW51529 EAW51530 Q99558 AA564389 AJ008135 AJ008136 AJ008137 AJ008138 AJ008139 AJ008140 AJ008141 AJ008142 AJ008143 AJ008144 AJ008145 AJ008146 AJ008147 AJ008148 AJ008149 AJ008150 AJ008151 AJ008152 AJ008153 AJ008156 AJ008157 AJ008158 AJ008159 AJ008160 AJ008161 AJ008162 AJ008163 AK123696 AK131438 BAD18584 AK290203 BAF82892 AK313085 BC022296 BC035576 AAH35576 BE645094 BU623799 CR749592 CAH18391 DA856801 DQ894064 ABM84990 HY096069 HY287427 Y10256 CAA71306 XM_011525441 XP_011523743 XR_934591 XR_951536 XR_952490 NM_003954 NP_003945
Function Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner. {ECO:0000269|PubMed:15084608}.
Subcellular Location Cytoplasm.
Tissue Specificity Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon. {ECO:0000269|PubMed:9020361}.
Top Pathways TNF signaling pathway, Apoptosis, Epstein-Barr virus infection, HTLV-I infection, Osteoclast differentiation

NIK CRISPR/Cas9 KO Plasmid (h) - sc-400620 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK HDR Plasmid (h) - sc-400620-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK Double Nickase Plasmid (h) - sc-400620-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK Double Nickase Plasmid (h2) - sc-400620-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK CRISPR Activation Plasmid (h) - sc-400620-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK CRISPR Activation Plasmid (h2) - sc-400620-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK Lentiviral Activation Particles (h) - sc-400620-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK Lentiviral Activation Particles (h2) - sc-400620-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIK siRNA (h) - sc-36065 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK shRNA Plasmid (h) - sc-36065-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK shRNA (h) Lentiviral Particles - sc-36065-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK siRNA (h2) - sc-44314 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK shRNA Plasmid (h2) - sc-44314-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK shRNA (h2) Lentiviral Particles - sc-44314-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIK/MAP3K14 RNAi - H00009020-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU024531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1137 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1136 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1135 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2185 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2185 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12670 from Sigma-Aldrich

Category miRNA

MAP3K14 siRNA (Human) - CRH5947 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAP3K14 (NM_003954.3) - SHH337667 from Creative biogene

Category siRNA
Species Reactivities Human

Human MAP3K14 siRNA - orb266449 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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