Gene Symbol | COLEC11 |
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Entrez Gene | 78989 |
Alt Symbol | 3MC2, CL-K1-I, CL-K1-II, CL-K1-IIa, CL-K1-IIb, CLK1 |
Species | Human |
Gene Type | protein-coding |
Description | collectin sub-family member 11 |
Other Description | Collectin K1|collectin kidney protein 1|collectin-11 |
Swissprots | A7VJJ5 J3KQY9 A7VJJ2 A1IGE5 A7VJJ3 Q5CZ85 A1IGE6 A7VJJ4 B2R9M5 B4E1G0 Q9BWP8 Q7Z6N1 A1IGE4 |
Accessions | AAY24235 CAS03503 CAS03504 CAS03505 CAS03506 CAS03507 CAS03509 CAS03510 CAS03511 EAX01052 EAX01053 EAX01054 EAX01055 Q9BWP8 AB119525 BAF43301 AB119650 BAF43302 AB119651 BAF43303 AB119652 BAF43304 AB119684 BAF79604 AB119685 BAF79605 AB119686 BAF79606 AB119687 BAF79607 AK303824 BAG64772 AK313840 BAG36572 AY358439 AAQ88805 BC000078 AAH00078 BC009951 AAH09951 BE259985 BF316908 BF740034 BM547424 CR936641 CAI56781 HQ447196 ADQ31683 XM_005263853 XP_005263910 XM_006711897 XP_006711960 NM_001255982 NP_001242911 NM_001255983 NP_001242912 NM_001255984 NP_001242913 NM_001255985 NP_001242914 NM_001255986 NP_001242915 NM_001255987 NP_001242916 NM_001255988 NP_001242917 NM_001255989 NP_001242918 NM_024027 NP_076932 NM_199235 NP_954705 NR_045659 |
Function | Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N- acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:17179669}. |
Top Pathways | Phagosome |
COLEC11 CRISPR/Cas9 KO Plasmid (h) - sc-413098 from Santa Cruz Biotechnology
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COLEC11 HDR Plasmid (h) - sc-413098-HDR from Santa Cruz Biotechnology
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COLEC11 Double Nickase Plasmid (h) - sc-413098-NIC from Santa Cruz Biotechnology
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COLEC11 Double Nickase Plasmid (h2) - sc-413098-NIC-2 from Santa Cruz Biotechnology
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COLEC11 CRISPR Activation Plasmid (h) - sc-413098-ACT from Santa Cruz Biotechnology
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COLEC11 CRISPR Activation Plasmid (h2) - sc-413098-ACT-2 from Santa Cruz Biotechnology
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COLEC11 Lentiviral Activation Particles (h) - sc-413098-LAC from Santa Cruz Biotechnology
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COLEC11 Lentiviral Activation Particles (h2) - sc-413098-LAC-2 from Santa Cruz Biotechnology
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COLEC11 siRNA (h) - sc-94909 from Santa Cruz Biotechnology
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COLEC11 shRNA Plasmid (h) - sc-94909-SH from Santa Cruz Biotechnology
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COLEC11 shRNA (h) Lentiviral Particles - sc-94909-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU061731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6410 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6410 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02657 from Sigma-Aldrich
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COLEC11 siRNA (Human) - CRJ2235 from Cohesion Biosciences
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COLEC11 - MBS8226992 from MyBioSource
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shRNA set against Human COLEC11 (NM_199235.2) - SHH267521 from Creative biogene
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COLEC11 shRNA Plasmid (Human) - CHJ2235 from Cohesion Biosciences
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COLEC11 miRNA 3'UTR clone - MiUTR4H-TG02264 from Creative biogene
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